lpat

PD 128042 (CI 976) is a potent, orally active, and selective ACAT inhibitor (IC50: 73 nM) as well as a lysophospholipid acyltransferase (LPAT) inhibitor. CI 976 inhibits Golgi-associated LPAT activity (IC50: 15 μM) and multiple membrane trafficking steps.

Velpatasvir (GS-5816), also known as GS-5816, is a potent and selective Hepatitis C virus NS5A inhibitor. GS-5816 has demonstrated pan-genotypic activity and a high barrier to resistance in HCV replicon assays. GS-5816 demonstrated pangenotypic antiviral activity in patients with genotype 1-4 HCV infection. It will be further evaluated in combination with other pangenotypic direct-acting antivirals to achieve the goal of developing a well-tolerated, highly effective treatment for all HCV genotypes.

Zilpaterol is an acting ß-agonist that causes fat loss and muscle gain in cattle.

Amezalpat is a PPARα antagonist with an IC50 of 58 nM [nanomolar]. Amezalpat also exhibits antitumor activity.

Zilpaterol hydrochloride is a agonist of β-adrenergic receptor (AR). It is used to increase the feeding efficiency and the size of cattle.

Zilpaterol-d7 (trans-(±)-Zilpaterol-d7) is a 2H-labeled Zilpaterol. Zilpaterol is a β-adrenergic receptor agonist, reducing marbling score by increasing muscle cross-sectional area and diluting intramuscular fat in beef cattle.

S-Zilpaterol-d7 is a deuterated compound of S-Zilpaterol.

Zilpaterol-d7 (Standard) is the standard substance of Zilpaterol-d7, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Zilpaterol-d7 (trans-(±)-Zilpaterol-d7) is a 2H-labeled Zilpaterol. Zilpaterol is a β-adrenergic receptor agonist, reducing marbling score by increasing muscle cross-sectional area and diluting intramuscular fat in beef cattle.

Geranylgeraniol (FT0626663) is an isoprenoid found in fruits, vegetables, and grains, including rice. Geranylgeraniol (FT0626663) inhibits growth and induces apoptosis of various tumor cells. Geranylgeraniol (FT0626663) protects monocytes against statin-induced cytotoxicity and suppresses the growth of Mycobacterium.

IACS-010759 hydrochloride is an orally potent and selective OXPHOS inhibitor that inhibits proliferation and induces apoptosis in OXPHOS-dependent brain cancer and acute myeloid leukaemia models for the study of relapsed/refractory AML and advanced solid tumours.