lpat

PD 128042 (CI 976) is a potent, orally active, and selective ACAT inhibitor (IC50: 73 nM) as well as a lysophospholipid acyltransferase (LPAT) inhibitor. CI 976 inhibits Golgi-associated LPAT activity (IC50: 15 μM) and multiple membrane trafficking steps.

Velpatasvir (GS-5816), also known as GS-5816, is a potent and selective Hepatitis C virus NS5A inhibitor. GS-5816 has demonstrated pan-genotypic activity and a high barrier to resistance in HCV replicon assays. GS-5816 demonstrated pangenotypic antiviral activity in patients with genotype 1-4 HCV infection. It will be further evaluated in combination with other pangenotypic direct-acting antivirals to achieve the goal of developing a well-tolerated, highly effective treatment for all HCV genotypes.

Zilpaterol is an acting ß-agonist that causes fat loss and muscle gain in cattle.

Amezalpat is an oral, potent, selective PPARα antagonist with an IC₅₀ of 58 nM and antitumor activity.

Zilpaterol hydrochloride is a agonist of β-adrenergic receptor (AR). It is used to increase the feeding efficiency and the size of cattle.

Lpathomab (LT3015; LT-3000) is a human IgG1 monoclonal antibody (mAb) targeting LPA. It reduces the release of cytokines IL-8 and IL-6 in SKOV3 cells and blocks tumor cell migration triggered by LPA. In Matrigel plug and CNV models, Lpathomab decreases angiogenesis. In the CCI mouse model, it inhibits brain injury. This compound can be utilized for research on brain injury, ovarian cancer, diabetic neuropathy, and spinal cord injury. Recommended isotype control: HumanIgG1kappa, Isotype Control.

Zilpaterol-D7 is a 2H-labeled Zilpaterol. Zilpaterol (T21539) is a β-adrenergic receptor agonist, reducing marbling score by increasing muscle cross-sectional area and diluting intramuscular fat in beef cattle.

S-Zilpaterol-D7 is a deuterated compound of S-Zilpaterol.

Zilpaterol-D7 (Standard) is the standard substance of Zilpaterol-D7, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Zilpaterol-D7 (trans- (±)-Zilpaterol-D7) is a 2H-labeled Zilpaterol. Zilpaterol (T21539) is a β-adrenergic receptor agonist, reducing marbling score by increasing muscle cross-sectional area and diluting intramuscular fat in beef cattle.

Zilpaterol‑13C3 hydrochloride (Standard) is a reference standard of Zilpaterol‑13C3 hydrochloride intended for quantitative analysis, quality control, and related biochemical research applications.

Velpatasvir-[13C2, D6] (Standard) is a reference standard of Velpatasvir-[13C2, D6] intended for quantitative analysis, quality control, and related biochemical research applications.

Geranylgeraniol (FT0626663) is an isoprenoid found in fruits, vegetables, and grains, including rice. Geranylgeraniol (FT0626663) inhibits growth and induces apoptosis of various tumor cells. Geranylgeraniol (FT0626663) protects monocytes against statin-induced cytotoxicity and suppresses the growth of Mycobacterium.

IACS-010759 hydrochloride is an orally potent and selective OXPHOS inhibitor that inhibits proliferation and induces apoptosis in OXPHOS-dependent brain cancer and acute myeloid leukaemia models for the study of relapsed/refractory AML and advanced solid tumours.