lipid

Lipid X is a monosaccharide precursor of E coli lipid A.This compound is unstable in powder form and other related salt forms are recommended.

Lipid A-11 is a lipid component of endotoxin that is primarily responsible for the toxic properties of gram-negative bacteria. Lipid A-11 constitutes the innermost region of the lipopolysaccharide (LPS) molecule, also known as endotoxin, and its hydrophobic nature facilitates anchoring of the LPS structure into the bacterial outer membrane. Lipid A-11 plays a critical role in host-pathogen interactions, contributing to septic shock and immunological activation during bacterial infections.

Kdo2-Lipid A ammonium (KLA) is a selective and potent TLR4 agonist, a lipopolysaccharide.Kdo2-Lipid A ammonium induces the release of TNF and PGE2.

Monophosphoryl lipid A (MPLA), also known as Glucopyranosyl lipid A, is an agonist of toll-like receptor 4. Derived from the cell wall of nonpathogenic Salmonella, MPLA is a valuable compound for research on immunization and vaccine development.

Lipid 5, an amino lipid compound, demonstrates proficient mRNA delivery in rodent and primate models, with favorable pharmacokinetics and minimal toxicity.

3D-Monophosphoryl Lipid A-5 (3D-MPLA-5) is a TLR agonist that can serve as an adjuvant in vaccines to enhance their immunogenicity.

Monophosphoryl Lipid A-12 is a reagent used in biochemical reactions.

3D-Monophosphoryl Lipid (12,16) is a reagent used in biochemical reactions.

Lifibrol (U-83860) is an inhibitor of cholesterol synthesis.Lifibrol has anticholesterol and hypolipidemic properties and promotes the conversion of LDL Apo B-100 in patients with hypercholesterolemia and mixed hyperlipidemia.

Mevastatin (ML236B) is an HMG-CoA reductase inhibitor that was initially isolated from the mold Pythium ultimum. Mevastatin was the first statin to enter clinical trials.

VK-28 is a brain permeable iron chelator with neuroprotection. VK-28 inhibits basal as well as iron-induced mitochondrial lipid peroxidation.

Lipid peroxidation inhibitor 1 is an inhibitor of lipid peroxidation (IC50: 0.07 μM).

Monophosphoryl lipid A (free acid) acts as an agonist for toll-like receptor 4. It is employed in immunological and vaccine research.

Hexa lipid 114 is an ionizable cationic lipid and a derivative of lipid 114.

Lipid U-101 is an ionizable cationic lipid extensively used in the formulation of lipid nanoparticles (LNPs) for mRNA delivery.

OA2 lipid is an ionizable lipid that can form single-component lipid nanoparticles (LNPs) for the delivery of RNA.

Glycolipids are lipids with a carbohydrate attached by a glycosidic (covalent) bond. Their role is to maintain the stability of the cell membrane and to facilitate cellular recognition, which is crucial to the immune response and in the connections that allow cells to connect to one another to form tissues.

3D-Monophosphoryl Lipid (14) is a reagent used in biochemical reactions.

Carvedilol phosphate hemihydrate (BM 14190 phosphate hemihydrate) is the phosphate salt form of carvedilol, a racemic mixture and adrenergic blocking agent with antihypertensive activity and no intrinsic sympathomimetic activity.

Carvedilol (SKF 105517) Phosphate is the phosphate salt form of carvedilol, a racemic mixture and adrenergic blocking agent with antihypertensive activity and devoid of intrinsic sympathomimetic activity. The S enantiomer of carvedilol nonselectively binds to and blocks beta-adrenergic receptors, thereby exerting negative inotropic and chronotropic effects, and leading to a reduction in cardiac output. In addition, both enantiomers of carvedilol bind to and block alpha 1-adrenergic receptors, thereby causing vasodilation and reducing peripheral vascular resistance.

Uric acid is an important antioxidant that scavenges oxygen radicals and reactive oxygen species (such as singlet oxygen and peroxynitrite), inhibits lipid peroxidation, helps maintain stable blood pressure, and is the final product of purine metabolism. It is commonly used to induce hypertension models.

Ceramides Mixture, an endogenous ceramide, consists of hydroxy and non-hydroxy fatty acid-containing ceramides. It is involved in the regulation of cell cycle arrest, growth inhibition, and modulation of telomerase activity.

NADPH tetrasodium salt is the reduced form of the electron acceptor nicotinamide adenine dinucleotide phosphate, which acts as an electron donor in a variety of biological reactions. NADPH tetrasodium salt is also an endogenous inhibitor of ferroptosis.

1,2-Distearoyl-sn-glycero-3-phosphorylcholine (L-ALPHA-PHOSPHATIDYLCHOLINE, DISTEAROYL) is a cylindrical-shaped lipid used to synthesize liposomes. 1,2-Distearoyl-sn-glycero-3-phosphorylcholine (L-ALPHA-PHOSPHATIDYLCHOLINE, DISTEAROYL) is the lipid component in the lipid nanoparticle (LNP) system.