ldh level

B355252 protects against cell death caused by glutamate-evoked oxidative stress. B355252 shows neuroprotective effect, potentiating nerve growth factor (NGF)-induced neurite outgrowth.

Nedosiran (DCR-PHXC) is a GalNAc-dsRNA conjugate designed for RNA interference–based silencing of lactate dehydrogenase (LDH), enabling selective hepatic targeting and reduction of oxalate production, Nedosiran is extensively studied as a potential therapeutic approach for patients with primary hyperoxaluria and end-stage renal disease to address metabolic dysregulation at the RNA level.