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lcrf 0004

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  • Inhibitors & Agonists
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    TargetMol | Inhibitors_Agonists
LCRF-0004
T711771229611-73-7
LCRF-0004 is a potent and selective RON receptor tyrosine kinase inhibitor. The RON receptor tyrosine kinase has been identified as an important mediator of KRAS oncogene addiction and is overexpressed in the majority of pancreatic cancers. Preclinical studies show that inhibition of RON function decreases pancreatic cancer cell migration, invasion, and survival and can sensitize pancreatic cancer cells to chemotherapy. RON receptor tyrosine kinase is a potential as a therapeutic target.
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6-8 weeks
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SCD1 Inhibitor
T711751231243-91-6
SCD1 Inhibitor is a novel stearoyl-CoA desaturase1 (SCD1) inhibitor.
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6-8 weeks
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