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khk-c

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  • Inhibitors & Agonists
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    TargetMol | Inhibitors_Agonists
Ketohexokinase inhibitor 1
PF-06835919
T156542102501-84-6
Ketohexokinase inhibitor 1 is a ketohexokinase inhibitor (IC50s: 8.4 nM and 66 nM for KHK-C and KHK-A, respectively).
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BI-9787
T200047
BI-9787 is a zwitterionic inhibitor of ketohexokinase (KHK), demonstrating IC50 values of 12 nM for hKHK-A and 12.8 nM for hKHK-C. It exhibits good metabolic stability in rat hepatocytes and favorable pharmacokinetic properties in vivo in rats.
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