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Results for "
khk-c
" in TargetMol Product Catalog.- Inhibitors & Agonists3
Ketohexokinase inhibitor 1
PF-06835919
T156542102501-84-6
Ketohexokinase inhibitor 1 is a ketohexokinase inhibitor (IC50s: 8.4 nM and 66 nM for KHK-C and KHK-A, respectively).
- $106
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GS-1291269
T2149142845278-33-1
GS-1291269 is a potent neutral ketohexokinase (KHK) inhibitor, exhibiting IC50 values of 0.38 nM for KHK-C and 2.1 nM for KHK-A. In a rat fructose challenge model, GS-1291269 effectively reduces fructose-1-phosphate (F1P) levels in the liver and kidneys. It is applicable in the study of renal diseases and metabolic dysfunction-associated steatotic liver disease (MASLD).
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