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jak-in-14

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  • Inhibitors & Agonists
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    TargetMol | Inhibitors_Agonists
JAK-IN-14
T97641973485-06-1
JAK-IN-14 (compound 16) is a specific JAK1 inhibitor with IC50<5 μM. It prevents JAK1 phosphorylation by binding to the active site of JAK1, and is more than 8-fold selective for JAK1 over JAK2 JAK3, and can be used in immune, inflammation and cancer research.
  • $81
In Stock
Size
QTY
jak-in-20
T635811654776-91-6
JAK-IN-20 is a potent, orally active, broad-based JAK inhibitor, effective on JAK1 (IC50: 7 nM), JAK2 (IC50: 5 nM), and JAK3 (IC50: 14 nM), exhibiting excellent pharmacokinetic and anti-inflammatory activity in vivo.
  • $1,520
6-8 weeks
Size
QTY