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Results for "

isgs

" in TargetMol Product Catalog
  • Inhibitors & Agonists
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    TargetMol | All_Pathways
  • Inhibitory Antibodies
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    TargetMol | Inhibitory_Antibodies
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    TargetMol | Recombinant_Protein
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RO8191
RO4948191, CDM-3008
T22142691868-88-9
RO8191 (CDM-3008) (CDM-3008) is an agonist of interferon (IFN) receptor.
  • $38
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TargetMol | Citations Cited
ChX710
T136132438721-44-7
ChX710 activates the type I interferon response to cytosolic DNA by priming specific Interferon-Stimulated Genes (ISGs), inducing the ISRE promoter sequence, and facilitating the phosphorylation of Interferon Regulatory Factor (IRF) 3.
  • $55
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Anti-IFNAR1 Antibody
T9901A-1269
Anti-IFNAR1 Antibody (Anifrolumab) is a humanized IgG1 kappa monoclonal antibody targeting the type I interferon receptor subunit 1 (IFNAR1). This product specifically binds to IFNAR1, blocking the interaction of all type I interferons (including all subtypes of IFN-alpha, IFN-beta, and IFN-omega) with the receptor complex. This inhibition blocks the activation of the downstream JAK/STAT signaling pathway, reduces the expression of interferon-stimulated genes (ISGs), and suppresses type I interferon-mediated immune responses.
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