hppd

HPPD-Q (HPPD-quinone) is a substituted p-benzoquinone and a derivative of 6-PPD-Q.

Sulcotrione is a β-triketone herbicide. It also can inhibit hydroxyphenylpyruvate dioxygenase.

Benzobicyclon is a 4-hydroxyphenylpyruvate dioxygenase (4-HPPD) inhibitor and herbicide that is spectrally active against annual grasses, sedges, and broadleaf weeds without toxicity to rice.

HPPD-IN-2 (compound 28) is an herbicide that functions as an HPPD inhibitor. It effectively targets AtHPPD and demonstrates increased safety when used on canola crops.

HPPD-IN-5 (compound IV-45) is an inhibitor of 4-hydroxyphenylpyruvate dioxygenase (HPPD) with an IC50 of 0.21 μM. It is utilized as a herbicide.

HPPD-IN-6 (Compound IIy) is a highly selective HPPD inhibitor for rice crops. It exhibits potent herbicidal activity against Echinochloa crus-galli and Leymus chinensis (including herbicide-resistant biotypes), with an EC50 range of 19.62-33.26 g of ai/ha. Effective at application rates of 90-150 g of ai/ha, HPPD-IN-6 is suitable for developing herbicides.

HPPD/PPO-IN-1 (Compound B14) functions as a dual inhibitor of both HPPD and PPO, exhibiting IC50 values of 0.12 μM for Arabidopsis thaliana HPPD and 0.51 μM for Nicotiana tabacum PPO. This compound demonstrates broad-spectrum herbicidal activity while being safe for use on peanut and cotton crops. HPPD/PPO-IN-1 is suitable for the development of environmentally friendly herbicides.

HPPD-IN-1 (compound II-3), a potent HPPD inhibitor, exhibits inhibitory activity against Arabidopsis thaliana HPPD (AtHPPD) with an IC50 of 0.248 μM, surpassing mesotrione's IC50 of 0.283 μM, and demonstrates excellent herbicidal efficacy against both broadleaf and monocotyledonous weeds [1].

HPPD-IN-3 (compound 25) serves as a potent inhibitor of 4-Hydroxyphenylpyruvate dioxygenase (HPPD) and exhibits greater efficacy than Mesotrione, featuring an IC50 of 10 nM [1].

HPPD-IN-4 (Compound III-29) serves as a selective HPPD inhibitor, demonstrating an IC 50 value of 0.19 μM. It is primarily utilized in research focused on high-efficiency herbicides [1].

Mesotrione is a selective triketone herbicide

AtHPPD-IN-1 (Compound III-15) is an HPPD inhibitor and herbicide with high safety for peanuts. It has an IC50 of 12 nM against Arabidopsis HPPD.

Cypyrafluone is a dual oxidase inhibitor of 4-hydroxyphenylpyruvate dioxygenase (4-HPPD), effectively blocking the production of homogentisic acid (HGA).

Iptriazopyrid (NC-656) is a triazole carboxamide herbicide that targets 4-hydroxyphenylpyruvate dioxygenase (HPPD). It exhibits a Ki value of 24.3 nM for Arabidopsis HPPD and 33.3 nM for rice HPPD. By inhibiting the synthesis of plastoquinone and carotenoids, Iptriazopyrid causes weed yellowing and death. It shows promise in research for controlling paddy field weeds such as barnyard grass.

Nitisinone-13C6 is intended for use as an internal standard for the quantification of nitisinone by GC- or LC-MS. Nitisinone (T1684) is an inhibitor of 4-hydroxyphenylpyruvate dioxygenase (HPPD), which converts 4-hydroxyphenylpyruvate (HPPA) to homogentisate in the tyrosine catabolic pathway.1Nitisinone increases urinary levels of HPPA and 4-hydroxyphenyllactate (HPLA) in rats when administered at a dose of 10 mg/kg. Nitisinone (T1684) (3 mg/kg) prevents the neonatal lethality of fumarylacetoacetate hydrolase (FAH) deficiency in mice when administered to pregnant dams.2It exhibits hepatoprotective effects inFAH-/-mice, such as prevention of increases in plasma levels of aspartate serine aminotransferase (AST) and conjugated bilirubin, when administration is continued following birth at a dose of 1 mg/kg. Nitisinone (T1684) (100 μg) decreases urinary excretion of homogentisate and increases urinary excretion of HPPA, HPLA, and 4-hydroxyphenylacetate in a mouse model of alkaptonuria induced by ethylnitrosourea.3Formulations containing nitisinone have been used in the treatment of hereditary tyrosinemia type 1 (HT-1).

Topramezone, a highly effective 4-hydroxyphenylpyruvate dioxygenase (4-HPPD) inhibitor, functions as a herbicide for the post-emergence eradication of broadleaf and grass weeds in corn [1].

Fenquinotrione, a 4-hydroxyphenylpyruvate dioxygenase (HPPD) inhibitor, exhibits IC50 values of 27.2 and 44.7 nM against HPPD from rice and Arabidopsis thaliana, respectively. As an herbicide, it effectively controls a wide spectrum of broadleaf and sedge weeds while demonstrating notable selectivity for rice [1].

Brassicanate A sulfoxide, isolated from Brassica oleracea [1], exhibits herbicidal properties by inhibiting the biosynthesis of essential amino acids in plants. It operates by binding to key enzymes such as dihydroxyacid dehydratase (DHAD), hydroxymethylpyruvate dioxygenase (HPPD), acetolactate synthase (ALS), PYL family proteins, and transport inhibitor response 1 (TIR1), thereby reducing their enzymatic activity.

Topramezone (Standard) is the standard substance of Topramezone, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Topramezone, a highly effective 4-hydroxyphenylpyruvate dioxygenase (4-HPPD) inhibitor, functions as a herbicide for the post-emergence eradication of broadleaf and grass weeds in corn .

Nitisinone-13C6 (Standard) is a reference standard of Nitisinone-13C6 intended for quantitative analysis, quality control, and related biochemical research applications. Nitisinone-13C6 is used as an internal standard when quantitatively analyzing nitisinone by gas chromatography-mass spectrometry or liquid chromatography-mass spectrometry. Nitisinone is an inhibitor of 4-hydroxyphenylpyruvate dioxygenase (HPPD), which converts 4-hydroxyphenylpyruvate (HPPA) to homovanillic acid during the tyrosine degradation pathway.