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Results for "
goslo-sr-5-69
" in TargetMol Product Catalog- Inhibitors & Agonists1
GoSlo-SR-5-69
T372941363419-31-1
GoSlo-SR-5-69 is a potent high-conductance calcium-activated potassium channel (BK channel) agonist, with an EC50 of 251 nM. GoSlo-SR-5-69 significantly shifts the voltage required for half-maximal activation in a negative direction (ΔV1/2 = −104 mV), thereby enhancing channel open probability. Widely used in studies of neuronal excitability, vasodilation, smooth muscle regulation, and ion channel pharmacology, it elucidates BK channel function under physiological and pathological conditions.
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