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By Target- Bcr-Abl
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By Target By ResearchField- Cancer(6)
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Results for "
gnf5
" in TargetMol Product Catalog- Inhibitors & Agonists7
- PROTAC Products4
GNF5-amido-Me
PROTAC ABL binding moiety 2
T18593778277-37-5
GNF5-amido-Me, the moiety based on GNF5 (ABL inhibitor),binds through a linker to the IAP ligand forming SNIPER[1].
- Inquiry Price
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GNF-5
GNF 5
T1803778277-15-9
GNF-5 is a specific non-ATP competitive inhibitor of Bcr-Abl (IC50: 0.22±0.1 uM, Wild-type Abl). It is an analog of GNF-2 with improved pharmacokinetic properties.
- $30
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QTY
GNF-5837
Cited
GNF 5837
T60971033769-28-6
GNF-5837 is a specific, and orally bioavailable pan-TRK inhibitor for TrkA/TrkB (IC50: 8/12 nM).
- $43
Size
QTY
CitedSNIPER(ABL)-013
T18684
SNIPER(ABL)-013, a compound that links GNF5 (ABL inhibitor) with Bestatin (IAP ligand) via a linker, effectively reduces BCR-ABL protein levels with a DC50 of 20 μM[1].
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SNIPER(ABL)-015
T18685
SNIPER(ABL)-015, a compound that conjugates GNF5 (ABL inhibitor) to MV-1 (IAP ligand) via a linker, effectively reduces BCR-ABL protein levels with a DC50 of 5 μM [1].
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SNIPER(ABL)-024
T186882222355-77-1
SNIPER(ABL)-024, a compound that conjugates GNF5 (ABL inhibitor) to an LCL161 derivative (IAP ligand) via a linker, effectively reduces BCR-ABL protein levels, achieving a half-maximal degradation concentration (DC50) of 5μM[1].
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