gdp-a-d-mannose disodium

GDP-α-D-mannose disodium gives a competitive inhibition with respect to GTP (Ki 14.7 μM) and an uncompetitive inhibition with respect to mannose-1-P (Ki 115 μM).GDP-α-D-mannose disodium is the donor substrate for mannosyltransferases and the precursor of

GDP-D-mannose disodium consists of GDP-α-D-mannose and GDP-β-D-mannose. GDP-α-D-mannose serves as a donor substrate for mannosyltransferases and a precursor for GDP-β-L-fucose biosynthesis. It competitively inhibits GTP with a Ki of 14.7 μM and non-competitively inhibits mannose-1-P with a Ki of 115 μM.