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By Target- Autophagy
- Bcl-2 Family(1)
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Results for "
gambogic acid b
" in TargetMol Product Catalog- Inhibitors & Agonists2
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Gambogic acid B
T82344887923-50-4
Gambogic acid B, isolated from Garcinia hanburyi resin, exhibits cytotoxic effects on A549, HCT116, and MDA-MB-231 cell lines with respective IC50 values of 1.60 µM, 6.88 µM, and 0.87 µM [1].
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Gambogic Acid
Cited
Guttic Acid, Guttatic Acid, Beta-Guttiferrin
T61852752-65-0
Gambogic Acid (Guttic Acid) ( EC50=0.78-1.64 uM) activates caspases. Gambogic Acid competitively suppresses Bcl-XL, Bcl-2, Bcl-W, Bcl-B, Bfl-1 and Mcl-1. The IC50s of Gambogic Acid for Bcl-XL, Bcl-2, Bcl-W, Bcl-B, Bfl-1 and Mcl-1 are 1.47, 1.21, 2.02, 0.66, 1.06 and 0.79 uM, respectively.
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