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g250e

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  • Inhibitors & Agonists
    2
    TargetMol | Inhibitors_Agonists
Vamotinib
PF-114
T637461416241-23-0In house
Vamotinib (PF-114) is an orally active and specific tyrosine kinase inhibitor with antiproliferative and antitumour activity.Vamotinib inhibits the phosphorylation of BCR ABL and BCR ABL-T315I, which promotes apoptosis. Vamotinib is used to study drug-resistant Philadelphia chromosome-positive (Ph+) leukaemia and Alzheimer's disease.
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6-8 weeks
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GNF-7
GNF7
T3196839706-07-9
GNF-7 is Bcr-Abl WT and Bcr-Abl T315I inhibitor with IC50 of 133 nM and 61 nM, respectively.
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