fitc

FITC (Fluorescein 5-isothiocyanate) is a derivative of fluorescein for the labeling of amines.

FITC-Dextran (MW 4000) is a marker composed of fluorescein isothiocyanate conjugated to 4 kDa dextran, widely used in microcirculation and cell permeability studies.

5(6)-FITC (Fluorescein isothiocyanate), or Fluorescein 5(6)-isothiocyanate, is a versatile amine-reactive derivative of fluorescein dye. It serves as an effective label for antibodies and other probes, finding utility in fluorescence microscopy, flow cytometry, and immunofluorescence-based assays such as ELISA and Western blotting.

FITC-Dextran (MW 10000) is a marker (10 kDa) formed by coupling FITC to dextran. FITC-Dextran is a labeled polysaccharide composed of branched glucose molecules of various lengths, enabling the determination of solute, ionic, and protein permeability of the blood-brain barrier depending on the size of the dextran used.

6-Fluorescein Isothiocyanate (6-FITC) is a fluorescein derivative widely employed in applications such as flow cytometry.

FITC-Dextran (MW 60,000-76,000) is a fluorescein isothiocyanate (FITC)-labeled dextran fluorescent probe that is commonly used as a tracer molecule to label and track the action of cells or other biomaterials on semipermeable membranes.

FITC-Dextran (MW 2,000,000) is a fluorescent dye-based compound that can be used for short cycle durations to outline blood vessels.FITC-Dextran (MW 2,000,000) is involved in the quantification of BBB leakage, and can be used in conjunction with a confocal microscope to visualize blood-brain-barrier leakage.

FITC-SAHA is a fluorescently-tagged derivative of suberoylanilide hydroxamic acid (SAHA), which acts as an inhibitor of histone deacetylases (HDAC). It is utilized in research related to cancer and Alzheimer's disease.

FITC-lysine-dextran, 500kDa, is a dextran conjugated with lysine and incorporates the fluorescent group FITC. Compared to dextran alone, lysine-dextran exhibits enhanced binding capacity for glutamic-plasminogen.

FITC-lysine-dextran, 4kDa, is a dextran compound conjugated with lysine and incorporates the fluorescent group FITC. Compared to dextran alone, lysine-dextran exhibits enhanced glutamic acid-plasminogen binding capacity.

FITC-lysine-dextran, 10kDa, is a dextran compound conjugated with lysine and contains the fluorescent group FITC. Lysine-dextran exhibits an enhanced ability to bind glutamic acid-plasminogen compared to dextran alone.

FITC-dextran sulfate, 40kDa, is a sodium sulfate dextran compound tagged with FITC, featuring an average molecular weight of 40 kDa.

FITC-inulin is an inulin labeled with FITC (Ex Em=488 525 nm) and is utilized for monitoring renal clearance.

FITC-lysine-dextran (70 kDa) is a dextran conjugated with lysine and contains the fluorescent moiety FITC. Lysine-dextran demonstrates enhanced glutamic acid-plasminogen binding capacity compared to dextran alone.

FITC-dextran sulfate, 500kDa is a sodium dextran sulfate labeled with FITC, with an average molecular weight of 500 kDa.

FITC-trehalose is a fluorescent derivative of trehalose. Trehalose is a naturally occurring α-linked 1,1-glucose disaccharide.

FITC-dextran sulfate, 10kDa, is a sodium dextran sulfate compound tagged with FITC, possessing an average molecular weight of 10 kDa.

Geldanamycin-FITC, a fluorescent probe derived from Geldanamycin, is applicable in fluorescence polarization assays to identify HSP90 inhibitors and can be employed to detect cell surface HSP90 [1] [2] [3]. It requires protection from light during storage.

Fmoc-Lys(5-FITC)-OH serves as a fluorescent marker for polypeptides and proteins, utilizing FITC—a pH and Cu^2+-sensitive dye—as its fluorescence probe for amine labeling [1] [2] [3].

FITC-β-Ala-β-Amyloid (25-35) is a FITC-labeled fluorescent compound employed in Alzheimer's disease research [1].

JQ1-FITC, a fluorescent BET bromodomain probe, exhibits high affinity binding to BRD4(BD1) and BRD4(BD2), with KD,app values of 6.5 nM and 5.8 nM respectively, as determined using GST-tagged BRD4 proteins in a CoraFluorTR-FRET assay; for BRD4(BD1), the value is 58.7 nM in a fluorescence anisotropy assay. It has excitation and emission maxima (λ) of 495 nm and 525 nm.

5(6)-Aminofluorescein (5(6)-AFM) is a high-purity, high-quality chemical utilized as a molecular probe and a significant fluorescent agent.

CGamF is a fluorescent probe designed for bile acid transport, consisting of a bile acid (Product No. 20250) linked to fluorescein via a glycine connecting group. In aqueous solution at pH 7.4, the excitation emission wavelengths of this probe are 492 515 nm, respectively. The fluorescence intensity of CGamF increases with rising pH when excited at 495 nm, while the intensity is unaffected by pH changes when excited at 440 nm. Sodium-dependent uptake of CGamF by hepatocytes increases with the concentration of the compound, with reduced absorption at lower sodium levels. CGamF has been utilized in vitro to study drug interactions and toxicity mediated by hepatic transporters.

CAY10731 is a fluorescent probe for hydrogen sulfide (H2S).[1] Upon reaction with H2S, fluorescein (FITC) is released and its fluorescence can be used to detect H2S. FITC displays excitation emission maxima of 485 535 nm, respectively. CAY10731 is selective for H2S over glutathione (GSH), cysteine, H2O3-, SO3-, and H2O2 as well as tBuO and OH radicals. It has been used to detect H2S in rat hippocampal slices and nematodes.