endoxifen (z isomer)

Endoxifen Z-isomer (EDX) is a key active metabolite of tamoxifen (TAM) with higher affinity and specificity to estrogen receptors that also inhibits aromatase activity.

Endoxifen Z-isomer hydrochloride (Endoxifen HCl) is the active metabolite of Tamoxifen, which is an effective and selective estrogen receptor antagonist.

Endoxifen E-isomer (E-Endoxifen) is the E-isomer of (Z)-Endoxifen. Endoxifen E-isomer has antiestrogenic effects.

Endoxifen E-isomer hydrochloride (E-Endoxifen hydrochloride), a tamoxifen metabolite, is an effective and specific Estrogen Response Modifier (SERM).

Endoxifen-d5 (Z-isomer) is the deuterium-labeled form of Endoxifen (Z-isomer). Endoxifen (Z-isomer) is an orally active metabolite of Tamoxifen, which exerts antiestrogenic effects in ERα-expressing breast cancer cells. It inhibits hERG in a concentration-dependent manner, with an IC50 of 1.6 μM.