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  • EGFR
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egfrin2

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  • Inhibitors & Agonists
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    TargetMol | Inhibitors_Agonists
EGFR-IN-2
T111591643497-70-4
EGFR-IN-2 is a non-covalent, orally available and mutation-selective EGFR inhibitor for the treatment of non-small cell lung cancer (NSCLC), with high selectivity for resistant single and double mutant T790M with IC50 = 27 nm to 33 nM, and low inhibitory activity for wild-type H292 (IC50 = 218 nM).
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6-8 weeks
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Mutated EGFR-IN-2
T121302050906-97-1
Mutated EGFR-IN-2 is an inhibitor of mutant-selective EGFR.
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6-8 weeks
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