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(1)
By Target- ADC Cytotoxin
- DNA Alkylation(1)
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Results for "
duocarmycin dm free base
" in TargetMol Product Catalog- Inhibitors & Agonists1
- ADC/ADC Related1
Duocarmycin DM free base
Duocarmycin
T111191116745-06-2
Duocarmycin DM free base is a potent DNA alkylator and antitumor antibiotic. It induces DNA damage via sequence-specific alkylation in the minor groove, commonly used as an ADC payload in cancer research.
- $288
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T73948
Duocarmycin DM, a toxin for antibody-drug conjugates (ADCs), functions as a DNA minor-groove alkylator. It exerts its anticancer activity through a distinct curved indole structure combined with a spirocyclopropylcyclohexadienone electrophile [1] [2].
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