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By Target- Factor Xa
- Thrombin(1)
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Results for "
du-176b
" in TargetMol Product Catalog- Inhibitors & Agonists3
Edoxaban Tosylate Monohydrate
edoxaban tosylate hydrate, DU-176b tosylate Monohydrate, DU-176b monohydrate
T23681229194-11-9
Edoxaban(DU-176) is an oral factor Xa (FXa) inhibitor in clinical development for stroke prevention.
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Edoxaban impurity 6
T37176480452-37-7
Edoxaban impurity 6 is an impurity of Edoxaban. Edoxaban (DU-176) is a selective, potent and orally active factor Xa (FXa) inhibitor with Kis of 0.561 nM and 2.98 nM for free FXa and prothrombinase, respectively. Edoxaban is an anticoagulant agent and can be used for stroke prevention[1][2]. [1]. Furugohri T, et al. DU-176b, a potent and orally active factor Xa inhibitor: in vitro and in vivo pharmacological profiles. J Thromb Haemost. 2008 Sep;6(9):1542-9.[2]. Mendell J, Lee F, Chen S, The Effects of the Antiplatelet Agents, Aspirin and Naproxen, on Pharmacokinetics and Pharmacodynamics of the Anticoagulant Edoxaban, a Direct Factor Xa Inhibitor. J Cardiovasc Pharmacol. 2013 Apr 23.
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Edoxaban hydrochloride
T64126480448-29-1
Edoxaban (DU-176b) hydrochloride is a potent, selective, orally active, direct inhibitor of Factor Xa (FXa), targeting human free FXa (Ki: 0.561 nM) and thrombinogenase (Ki: 2.98 nM). Over 10,000 times more selective than other thrombinases, it is suitable for studies to prevent thromboembolic disease.
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