diacylglycerol

DSPS (Dioctadecanoylphosphatidylserine) is a glycerophospholipid, an important phospholipid membrane component that plays a key role in cell cycle signaling. DSPS can regulate cellular activity and mediate apoptosis. DSPS is widely used as a nutritional supplement.

Digalactosyldiacylglycerol is a natural product for research related to life sciences. The catalog number is TN5814 and the CAS number is 145033-48-3.

Monogalactosyldiacylglycerol (MGDG), a polar lipid not forming bilayers, is located in the chloroplast thylakoid of aerobic photosynthetic organisms. This uncharged and highly unsaturated galactolipid creates a fluid environment aiding electron transfer diffusion in photosynthesis and can be used in natural protein packaging. Additionally, MGDG exhibits anti-inflammatory effects in vivo [1] [2].

Xanthohumol, also known as 2', 4, 4'-trihydroxy-6'-methoxy-3'-prenylchalcone or desmethylxanthohumol, is a member of the class of compounds known as 3-prenylated chalcones. It inhibits COX-1 and COX-2 activity and shows chemopreventive effects.

2-Furoic acid (Furan-2-carboxylic acid) reduces serum cholesterol and triglyceride levels and exhibits anti-lipidemic effects.

Phenylpyropene A is a fungal metabolite originally isolated from P. griseofulvum that has enzyme inhibitory and insecticidal activities.1,2,3 It inhibits acyl-coenzyme A:cholesterol acyltransferase (ACAT; IC50 = 0.8 μM).1 Phenylpyropene A inhibits diacylglycerol acyltransferase (DGAT) in rat liver microsomes (IC50 = 78.7 μM). It induces mortality in 100% of M. persicae when used at a concentration of 5 ppm.3 |1. Kwon, O.E., Rho, M.C., Song, H.Y., et al. Phenylpyropene A and B, new inhibitors of acyl-CoA: Cholesterol acyltransferase produced by Penicillium griseofulvum F1959. J. Antibiot. (Tokyo) 55(11), 1004-1008 (2002).|2. Lee, S.W., Rho, M.C., Choi, J.H., et al. Inhibition of diacylglycerol acyltransferase by phenylpyropenes produced by Penicillium griseofulvum F1959. J. Microbiol. Biotechnol. 18(11), 1785-1788 (2008).|3. Horikoshi, R., Goto, K., Mitomi, M., et al. Identification of pyripyropene A as a promising insecticidal compound in a microbial metabolite screening. J. Antibiot. (Tokyo) 70(3), 272-276 (2017).

Eicosapentaenoic acid methyl ester, a degradation product from monogalactosyl diacylglycerol, is an apoptosis-inducing anticancer compound.

1-Stearoyl-2-arachidonoyl-sn-glycerol (DAG) is a diacylglycerol (DAG) substrate that can be hydrolyzed to 2-arachidonic acid glycerol. 1-Stearoyl-2-arachidonoyl-sn-glycerol activates PKC, induces Ca2+ influx, and can induce tracheal smooth muscle contraction.

1,2-Dipalmitoyl-sn-glycerol ((S)-1,2-Dipalmitin) is an analog of the PKC-activating second messenger diacylglycerol (DAG). It weakly activates PKC.

Cochlioquinone A is an inhibitor of diacylglycerol kinase (DGK) and diacylglycerol acyltransferase (DGAT). It has been shown to reduce the concentration of phosphatidic acid in T cell lymphoma and has also been shown to compete with macrophage inflammatory protein-1α for binding to human CCR5 chemokine receptors.

1-Methyl-2-[(4Z,7Z)-4,7-tridecadienyl]-4(1H)-quinolone, a diacylglycerol acyltransferase inhibitor and angiotensin II receptor blocker, exhibits IC50 values of 20.1 μM and 34.1 μM, respectively, and demonstrates significant anti-Helicobacter pylori activity with a minimum inhibitory concentration (MIC) of 10 μg/mL [1] [2] [3].

Eicosapentaenoic acid methyl ester (Standard) is the standard substance of Eicosapentaenoic acid methyl ester, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Eicosapentaenoic acid methyl ester is a degradation product derived from monogalactosyl diacylglycerol, which is an apoptosis-inducing anticancer compound.

Roselipin 1B exhibits inhibitory effects on diacylglycerol acyltransferase (DGAT) in rats.

15:0-18:1 DG is a form of diacylglycerol (DAG). It is produced by the hydrolysis of triacylglycerol (TAG) found in butter. This compound shows potential for research in obesity, cardiovascular diseases, and dietary interventions.

1-Oleoyl-2-linoleoyl-sn-glycerol is a diacylglycerol (DG) that can activate protein kinase C (PKC), initiating downstream signaling cascades that promote tumor growth. This compound shows potential for use in breast cancer research.

Roselipin 2B inhibits diacylglycerol acyltransferase (DGAT) in rats.

Roselipin 1A inhibits diacylglycerol acyltransferase (DGAT) in rats.

1-Palmitoyl-2-linoleoyl-sn-glycerol is a diacylglycerol (DAG) lipid signaling molecule that can be found in the coralloid roots of the plant Cycas revoluta.

Amidepsin B is an inhibitor of diacylglycerol acyltransferase (DGAT).

Amidepsin C is an inhibitor of diacylglycerol acyltransferase (DGAT).

1,2-Di-(9Z-hexadecenoyl)-sn-glycerol (Compound 2e) is a diacylglycerol derivative isolated from the fungus Stereum Hirsutum. It exhibits potential thrombin inhibitory activity and may be useful in antithrombotic research.

5-Methylcytosine is a methylated nucleotide base found in eukaryotic DNA. It is an epigenetic modification formed by the action of DNA methyltransferases.

Kushenol K is a potent and Selective Inhibitor of cGMP Phosphodiesterase 5, it also has inhibitory effects on diacylglycerol acyltransferase (DGAT). Kushenol K shows weak antiviral activity against Herpes simplex virus types I and II.

7beta-(3-Ethyl-cis-crotonoyloxy)-1alpha-(2-methylbutyryloxy)-3,14-dehydro-Z-notonipetranone shows diacylglycerol acyltransferase (DGAT)1 inhibition with IC(50) values of 47.0 microM (for rat liver microsomes) and 160.7 microM (for HepG2 cell microsomes),