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- Immunology/Inflammation related(1)
- Nrf2(1)
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Results for "
dehydrocurdione
" in TargetMol Product Catalog.- Inhibitors & Agonists1
- Natural Products1
Dehydrocurdione
TN686738230-32-9
Dehydrocurdione is a sesquiterpene derived from zedoary with potent anti-inflammatory and antioxidant properties. It functions as a specialized inducer of Heme Oxygenase (HO)-1 by interacting with Keap1 via a Michael addition reaction involving its α, β-unsaturated carbonyl group. This leads to the nuclear translocation of Nrf2 and activation of the HO-1 E2 enhancer, effectively suppressing LPS-induced NO release.
- $143
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