datp

2'-Deoxyadenosine-5'-triphosphate trisodium (dATP trisodium) is a nucleotide substrate for DNA polymerase, essential for DNA synthesis and replication in cells.

2'-Deoxyadenosine-5'-triphosphate (Deoxyadenosine 5-triphosphate) (dATP) is a naturally occurring small molecule nucleotide used in cells for DNA synthesis or replication. 2'-Deoxyadenosine-5'-triphosphate (dATP) is a substrate for DNA polymerase. 2'-Deoxyadenosine-5'-triphosphate (dATP) is an inhibitor of RNA through an inactive alpha4beta4 quaternary structure. Deoxyadenosine-5'-triphosphate inhibits RNA through the inactive α4beta4 quaternary structure.2'-Deoxyadenosine-5'-triphosphate has been associated with cardiomyocyte growth.

7-Deaza-7-propargylamino-dATP, a deoxyadenosine triphosphate (dATP) analog, is utilized in gene sequencing.

7-Deaza-7-propargylamino-3'-azidomethyl-dATP, an analog of deoxyadenosine triphosphate (dATP), is widely used in next-generation sequencing (NGS).

Cy5-dATP is a Cy5 -labeled dATP . Cy5-dATP can be incorporated into a DNA primer [1] [2] .

6-PhEt-dATP is an ATP analog that specifically enhances the functionality of certain CFTR mutants, making it useful for cystic fibrosis research.

3′-O-Azidomethyl-dATP sodium solution (100mM) is a labeled and modified deoxyoligonucleotide (dNTP) that can release pyrophosphate to produce fluorescence, with specialized applications in gene synthesis and sequencing.

3'-ONH2-dATP sodium solution (100mM) is a labeled and modified deoxynucleotide (dNTP) that generates fluorescence through pyrophosphate release, making it particularly useful in gene synthesis and sequencing applications.

3'-P-dATP sodium is a labeled and modified deoxyoligonucleotide (dNTP) that can release pyrophosphate and generate fluorescence during gene synthesis and sequencing, so it has special application value.

3'-O-Methylthiomethyl-dATP sodium is a labeled and modified deoxyoligonucleotide (dNTP) that can release pyrophosphate and generate fluorescence during gene synthesis and sequencing, so it has special application value.

ddATP is a dideoxynucleotide, used as a chain extension inhibitor for DNA polymerase, and used for DNA sequencing by the Sanger method.

ddATP (2',3'-Dideoxyadenosine 5'-triphosphate) tetrasodium is an active metabolite of 2',3'-dideoxyinosine and functions as a chain elongation inhibitor for DNA polymerase. It is utilized in DNA sequencing using the Sanger method and in research related to viral infections.

TFE-IDAtp1-LinA is an efficient amphiphilic carrier that contains a trifluoroethyl imino diacetic acid analogue with Stp. It forms nanoparticles with Cas9 RNP ssDNA, facilitating the knockout of enhanced green fluorescent protein, with an ED50 of 0.38 nM Cas9 sgRNA ribonucleoprotein (RNP).

7-Deaza-7-propargylamino-ddATP, an analog of ddATP, serves as a viable option for gene sequencing purposes due to its chemical composition.

DATPT is a small molecule 12WLVSKF17 peptide mimetic molecule.DATPT inhibits SNX9-p47phox interactions and inhibits the production of reactive oxygen species and inflammatory cytokines.DATPT has anti-inflammatory and antimicrobial activity and acts by decreasing ATP production.DATPT is a potential compound for the treatment of sepsis.

3′-Azido-ddATP sodium, a modified labeled deoxyoligonucleotide (dNTP), releases pyrophosphate to generate fluorescence and is specifically utilized in gene synthesis and sequencing.

dATPαS sodium is a labeled and modified deoxyoligonucleotide (dNTP) that releases pyrophosphate to produce fluorescence, offering unique applications in gene synthesis and sequencing.

3'-NH2-ddATP sodium is a labeled and modified deoxyoligonucleotide (dNTP) that can release pyrophosphate and generate fluorescence during gene synthesis and sequencing, so it has special application value.

Fludarabine Phosphate (NSC 312887 Phosphate) is the phosphate salt of a fluorinated nucleotide antimetabolite analog of the antiviral agent vidarabine (ara-A) with antineoplastic activity. Fludarabine phosphate is rapidly dephosphorylated to 2-fluoro-ara-A and then phosphorylated intracellularly by deoxycytidine kinase to the active triphosphate, 2-fluoro-ara-ATP. This metabolite may inhibit DNA polymerase alpha, ribonucleotide reductase, and DNA primase, thereby interrupting DNA synthesis and inhibiting tumor cell growth.

2'-Deoxyadenosine-5'-triphosphate (dATP) is a purine nucleotide and derivative of the nucleic acid adenosine 5'-triphosphate .1dATP is a substrate for DNA polymerase in the synthesis of DNA.2It is a noncompetitive inhibitor of ribonucleotide reductases, which provides feedback inhibition during DNA synthesis.1dATP has commonly been used in DNA synthesis, sequencing, and labeling in research applications.3,4dATP accumulates in adenosine deaminase deficiency, a disorder characterized by mutations in the gene for adenosine deaminase, the enzyme that catalyzes the deamination of adenosine and deoxyadenosine.5 1.Berg, J.M., Tymoczko, J.L., and Stryer, L.Key steps in nucleotide biosynthesis are regulated by feedback inhibitionBiochemistry(2002) 2.Berg, J.M., Tymoczko, J.L., and Stryer, L.DNA is replicated by polymerases that take instructions from templatesBiochemistry(2002) 3.Cadwell, R.C., and Joyce, G.F.Randomization of genes by PCR mutagenesisPCR Methods Appl.2(1)28-33(1992) 4.Steffens, D.L., Jang, G.Y., Sutter, S.L., et al.An infrared fluorescent dATP for labeling DNAGenome Res.5(4)393-399(1995) 5.Flinn, A.M., and Gennery, A.R.Adenosine deaminase deficiency: A reviewOrphanet J. Rare Dis.13(1)65(2018)

Tenofovir diphosphate (TFV-DP) is a competitive inhibitor of DNA polymerases, specifically targeting dATP, and functions as a substrate for the reverse transcriptase (RT) of human immunodeficiency virus type 1 (HIV-1)[1].

TAS1553 is a highly effective, orally bioavailable protein-protein interaction (PPI) inhibitor with an IC50 value of 0.0396 μM. It effectively hinders DNA replication and diminishes the intracellular dATP pool. Moreover, TAS1553 induces apoptosis, making it a valuable compound in cancer research [1].

2'-Deoxy-2'-fluoroadenosine-5'-O-triphosphate is a fluorinated analog of ATP, the pivotal energy substrate for cellular metabolism, and acts as an inhibitor of E. coli RNA polymerase (Ki = 200 µM).