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  • Cytochromes P450
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cyp46a1

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    4
    TargetMol | Inhibitors_Agonists
Cholesterol 24-hydroxylase-IN-1
T607961613480-70-8In house
Cholesterol 24-hydroxylase-IN-1 is an orally active, selective, and potent inhibitor of cholesterol 24-hydroxylase (CH24H or CYP46A1) that crosses the blood-brain barrier.Cholesterol 24-hydroxylase-IN-1 may be useful in the study of epilepsy-like neurological disorders. Cholesterol 24-hydroxylase-IN-1 is used to study epilepsy-like neurological diseases.
  • $44
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CHL2310
T205330
CHL2310 is an inhibitor of CYP46A1 with an IC50 of 0.11 nM and a Kd of 0.37 nM. It is capable of crossing the blood-brain barrier. When labeled with radioactive [18F], CHL2310 can serve as a PET imaging agent.
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Cholesterol 24-hydroxylase-IN-2
T827311613481-52-9
Cholesterol 24-hydroxylase-IN-2, a potent inhibitor of cholesterol 24-hydroxylase (CH24H or CYP46A1), exhibits an IC50 value of 5.4 nM and has potential applications in mammalian imaging of this enzyme [1].
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8-10 weeks
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Soticlestat
TAK-935, OV935
T89371429505-03-2
Soticlestat (OV935) is a potent, selective and orally active cholesterol 24-hydroxylase (CYP46A1) inhibitor. It has the potential for epilepsy syndromes research.
  • $60
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