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cr 1 31 b

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  • Inhibitors & Agonists
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    TargetMol | Inhibitors_Agonists
CR-1-31-B
T387531352914-52-3
CR-1-31-B, a synthetic rocaglate, acts as a highly potent inhibitor of eIF4A. By disrupting the interaction between eIF4A and RNA, it effectively obstructs the initiation phase of protein synthesis. Specifically, CR-1-31-B interferes with the association between Plasmodium falciparum eIF4A (PfeIF4A) and RNA. Additionally, CR-1-31-B induces apoptosis in neuroblastoma and gallbladder cancer cells [4].
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8-10 weeks
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