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Results for "

col18a 1

" in TargetMol Product Catalog
  • Recombinant Protein
    3
    TargetMol | Recombinant_Protein
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COL18A1 Protein, Human, Recombinant (GST)
Collagen alpha-1(XVIII) chain, COL18A1
TMPH-01117
Expression system: E. coli
Length: 1578-1754, Partial
Activity: Not Tested
  • Inquiry Price
20 days
Size
QTY
Buffer-exchangeable
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COL18A1 Protein, Human, Recombinant (His)
Collagen alpha-1(XVIII) chain, COL18A1
TMPH-01118
Expression system: P. pastoris (Yeast)
Length: 1578-1754, Partial
Activity: Not Tested
  • Inquiry Price
20 days
Size
QTY
Buffer-exchangeable
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Endostatin Protein, Mouse, Recombinant (His)
type XVIII, Endostatin, collagen α-1(XVIII)chain, collagen alpha-1(XVIII)chain, collagen, COL18A1, antiangiogenic agent
TMPJ-00948
Endostatin, an endogenous non‑glycosylated inhibitor of endothelial cell proliferation and angiogenesis. It is produced and or trimmed by metalloproteinases such as MMP‑2 and MMP‑9, and cathepsins S, B and L. The N‑terminal ~27 aa of Endostatin appear to contain the majority of its activity. This region contains zinc binding sites that are thought to be critical for its anti‑endothelial and anti‑tumor effects, as well as multiple cleavage sites that, when used, can modify its activity. Mouse Endostatin shares 96% aa sequence identity with rat and 85‑87% with human, bovine and equine Endostatin. It is predominantly expressed in liver, kidney, lung, skeletal muscle and testis. Endostatin inhibits endothelial cell growth by inducing cell cycle arrest in G1 phase and initiating apoptosis. It is also thought to down‑regulate angiogenesis by blocking VEGF‑induced endothelial cell migration. Endostatin may also be involved with down‑regulation of angiogenesis after establishment of placental circulation in the pregnant uterus.
  • Inquiry Price
7-10 days
Size
QTY
SPR-compatible buffer