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Results for "
chk-1-in-4
" in TargetMol Product Catalog- Inhibitors & Agonists2
FLT3/CHK1-IN-1
T82393
Compound 18, also known as FLT3 CHK-IN-1, is a dual inhibitor targeting FLT3 and CHK1, exhibiting over 1700-fold selectivity towards c-KIT and significantly diminishing hERG affinity, with an IC50 of 58.4 μM. It demonstrates efficacy in suppressing tumor growth in mouse xenotransplantation models implanted with MV-4-11 cells [1].
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