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(1)
By Target- Antifolate
- Apoptosis(1)
- DHFR(1)
- HDAC(1)
- Microtubule Associated(1)
- Mitochondrial Metabolism(1)
- Others(3)
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Results for "
ch 150
" in TargetMol Product Catalog- Inhibitors & Agonists3
CH-1504
MobileTrex, CH 1504
T27002238074-89-0
CH-1504, dihydrofolate reductase (DHFR) inhibitor, is used potentially for the treatment of rheumatoid arthritis.
- $1,520
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QTY
Tubulin/HDAC-IN-1
T615242413587-26-3
Tubulin/HDAC-IN-1 is a dual inhibitor of tubulin and HDAC8, interacting with tubulin via CH/π interactions and with HDAC8 through hydrogen bonds. It effectively inhibits tubulin polymerization and selectively targets HDAC8 with an IC50 of 150 nM. Additionally, Tubulin/HDAC-IN-1 demonstrates cytotoxicity against various human cancer cells, induces cell cycle arrest in the G2/M phase, and triggers cell apoptosis, making it valuable for studying hematologic and solid tumors, including neuroblastoma and leukemia [1].
- $1,520
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