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axitinib

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  • Inhibitors & Agonists
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    TargetMol | Inhibitors_Agonists
Axitinib
AG-013736
T1452319460-85-0
Axitinib (AG-013736) is a multi-targeted tyrosine kinase inhibitor that inhibits VEGFR1, VEGFR2, VEGFR3, and PDGFRβ (IC50=4 20 0.4 2 nM). Axitinib has antitumor activity and is used in the treatment of renal cell carcinoma.
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TargetMol | Inhibitor Hot
Axitinib sulfoxide
Axitinib metabolite M12,PF-03482595,AG-028458
T211291347304-18-0
Axitinib sulfoxide is a major metabolite of Axitinib, which is a VEGFR tyrosine kinase inhibitor and may be useful in cancer therapy.
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