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By Target- 5-HT Receptor
- MT Receptor(1)
- Melatonin Receptor(1)
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Results for "
anti-immobility
" in TargetMol Product Catalog- Inhibitors & Agonists2
Luzindole
N-0774
T15795117946-91-5
Luzindole (N-0774) is a selective melatonin receptor antagonist that inhibits experimental autoimmune encephalomyelitis and exhibits antidepressant-like activity. It preferentially targets MT2 (Mel1b) over MT1 (Mel1a), with Ki values of 10.2 nM for human MT2 and 158 nM for MT1.
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SR 57227 hydrochloride
SR 57227A, SR 57227 hydrochloride
T2339477145-61-0
SR 57227 hydrochloride(SR 57227A ) is a potent, orally active and selective 5-HT3 receptor agonist. It with ability to cross the blood brain barrier. It has affinities (IC50) varying between 2.8 and 250 nM for 5-HT3 receptor binding sites in rat cortical membranes and on whole NG 108-15 cells or their membranes. Anti-depressant effects.
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