aggression

Tetrabenazine (Ro 1-9569) is a former antipsychotic drug used to treat various movement disorders. It inhibits neurotransmitter uptake into adrenergic storage vesicles and serves as a high-affinity label for the vesicle transport system.

Tiapride is a selective blocker of D2 3 dopamine receptors in the brain. It is used in the therapy of various psychiatric and neurological disorders containing dyskinesia, negative symptoms of psychosis, alcohol withdrawal syndrome, and aggression and agitation in the elderly.

(S)-Norfluoxetine, the S enantiomer of Norfluoxetine, functions as a selective serotonin reuptake inhibitor. It enhances allopregnanolone levels and reduces aggression in socially isolated mice.

2-Methylhexacosane is a saturated hydrocarbon and an insect pheromone. It has been found in the cuticle of M. dasystomus females, but not males, contributing to the mating behavior of males, as well as in D. melanogaster females where it modulates male aggression. 2-Methylhexacosane has also been found in yellow jacket (V. vulgaris) trail extracts.

Eltoprazine dihydrochloride is a drug that had previously been developed for aggression, has recently been investigated for L-DOPA-induced dyskinesia in animal models of Parkinson´s disease (PD) and in dyskinetic PD patients.