acidic-ph

4-Nitrophenyl α-D-galactopyranoside (PNP-alpha-D-Gal) is an artificial substrate of 4-nitrophenyl (pNP) glycopyranoside used for detecting α-galactosidase activity. The amount of released pNP increases significantly when PNP-alpha-D-Gal is used as a substrate.

1O14 is an ionizable lipid. Its ability to form unstable non-bilayer structures at acidic pH is crucial for endosomal escape and RNA cytosolic delivery. 1O14 is applicable in the preparation of liposomes.

IAJD93 is an ionizable lipid. Its ability to form unstable non-bilayer structures at acidic pH is crucial for endosomal escape and RNA delivery into the cytosol. IAJD93 can be utilized in the preparation of liposomes.

IAJD249 is an ionizable lipid. This type of lipid is crucial for endosomal escape and the delivery of RNA into the cytosol, due to its ability to form unstable non-bilayer structures at acidic pH. IAJD249 is also utilized in the preparation of liposomes.

Al-28 is an ionizable lipid that plays a crucial role in endosomal escape and RNA cytosol delivery by forming unstable non-bilayer structures at acidic pH. This compound is utilized in the preparation of liposomes.

L16 is an ionizable lipid. The ability of ionizable lipids to form unstable non-bilayer structures at acidic pH is crucial for endosomal escape and RNA cytosolic delivery. L16 can be utilized in liposome preparation.

306Oi9-cis2 is an ionizable lipid. The ability of ionizable lipids to form unstable non-bilayer structures at acidic pH is crucial for endosomal escape and RNA cytosolic delivery. 306Oi9-cis2 is utilized in the preparation of liposomes.

RM 137-15 is an ionizable lipid. Its ability to form unstable non-bilayer structures under acidic pH is crucial for endosomal escape and RNA cytosol delivery. RM 137-15 is utilized in the preparation of liposomes.

DSPE-PEG1000-TH is a PEG compound composed of DSPE and a pH-responsive cell-penetrating peptide (TH). In acidic environments, such as the tumor microenvironment, TH is activated, enabling the selective delivery of small molecules, oligonucleotides, proteins, and other agents into tumor cells.

DSPE-PEG5000-TH is a PEG compound formed from DSPE and the pH-responsive cell-penetrating peptide (TH). In acidic environments like the tumor microenvironment, TH is activated, allowing it to selectively deliver small molecules, oligonucleotides, proteins, and similar substances into tumor cells.

DSPE-PEG2000-TH is a PEG conjugate made from DSPE and a pH-responsive cell-penetrating peptide (TH). In acidic environments—such as the tumor microenvironment—TH becomes activated, allowing for the selective delivery of small molecules, oligonucleotides, and proteins into tumor cells.

Sodium sesquicarbonate hydrate is a compound with buffering activity, capable of stabilizing pH by neutralizing acidic substances without causing drastic changes. This characteristic makes it widely used in various fields, particularly notable for its effectiveness in maintaining acid-base balance within biological systems.