ac-tubulin

BRD73954, an effective and specific HDAC inhibitor, which is with IC50 of 36 nM and 120 nM for HDAC6 and HDAC8, respectively.

Ombrabulin hydrochloride is a synthetic, selective CA-4 phosphate ester or derivative of Ombrabulin to disrupt the tubulin cytoskeleton of endothelial cells and has antivascular effects. Ombrabulin is a tubulin polymerizing inhibitor, a member of the combretastatin A-4 compound class, which is a water-soluble tubulin depolymerizing tumor vascularizing compound.

Ombrabulin is a derivative of CA-4 phosphate. It is known to show antivascular effects through selective disruption of the tubulin cytoskeleton of endothelial cells.

AC-93253 iodide is a selective inhibitor of SIRT2. It significantly enhances the acetylation of tubulin p53 and histone H4.

Ac-Lys-Val-Cit-PABC-MMAE is a conjugate consisting of an antibody-drug conjugate (ADC) linker (peptide Ac-Lys-Val-Cit-PABC) and the cytotoxic agent monomethyl auristatin E (MMAE), a potent tubulin polymerization inhibitor [1].

Ac-Lys-Val-Cit-PABC-MMAE (formic) is an agent-linker conjugate used in antibody-drug conjugates (ADCs), consisting of a peptide linker (Ac-Lys-Val-Cit-PABC) attached to the cytotoxic agent Monomethyl auristatin E (MMAE), a potent inhibitor of tubulin polymerization[1].