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(2)
By Target- Bcr-Abl
- Apoptosis(1)
- FLT(1)
- Src(1)
- Others(1)
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Results for "
abl1t315i
" in TargetMol Product Catalog- Inhibitors & Agonists3
Rebastinib
DCC-2036, DCC2036, DCC 2036
T26401020172-07-9
DCC-2036 (Rebastinib (DCC-2036)) is a conformational control Bcr-Abl inhibitor for Abl1(WT, IC50: 0.8 nM) and Abl1(T315I, IC50: 4 nM), also inhibits LYN, SRC, HCK, FGR, FLT3, KDR, and Tie-2, and low activity to c-Kit. Rebastinib aimed at the Angiopoietin2-Tie2 pathway.
- Inquiry Price
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QTY
BCR-ABL-IN-2
T10489897369-18-5
BCR-ABL-IN-2 is a BCR-ABL1 tyrosine kinase inhibitor (IC50s: 57 nM, 773 nM for ABL1 native and ABL1 T315I).
- Inquiry Price
Size
QTY
Vodobatinib
K-0706
T88821388803-90-4
Vodobatinib (K-0706) is a novel 3rd generation (3G) TKI effective against wild-type and mutated BCR-ABL1 with limited off-target activity.
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