a,a-trehalose 6-phosphate potassium

Trehalose 6-phosphate potassium salt hydrate (α,α-Trehalose 6-phosphate potassium salt hydrate) is a Trehalose derivative, an intermediate in trehalose biosynthesis, and an important signaling metabolite in plants. It can regulate root branching through the master kinase SNF1-related kinase-1 (SnRK1) and rapamycin target (TOR).

α,α-Trehalose 6-phosphate potassium is a glucose analogue with potent anti-hyperglycemic activity. It serves as a central signaling molecule in carbon metabolism regulation, particularly in plants and microorganisms, where it functions as a sensor for sucrose or glucose levels. In vivo, Tre6P is rapidly converted to its end product, α,α'-trehalose, by the enzyme α,α-Trehalose 6-phosphate phosphatase (T6PP). Beyond its role as a metabolic intermediate, Tre6P demonstrates potential in diabetic models to alleviate hyperglycemic symptoms by modulating glucose homeostasis.