T8735

Cytidine 5′-diphosphat (5'-CDP) is synthesized from cytidine monophosphate (CMP) or uridine monophosphate (UMP) by the transfer of phosphoryl group, catalyzed by the enzyme uridylate kinase (UMPK).

S16–1029 is a selective, orally active butyrylcholinesterase (BChE) inhibitor with IC50 values of 11.35 nM for eqBChE and 48.1 nM for hBChE. It can cross the blood-brain barrier (BBB) and reach the central nervous system (CNS), making it suitable for Alzheimer's disease (AD) research [1].

SAG-524 is a powerful oral small molecule that inhibits HBV viral replication. In HepG2.2.15 cells, SAG-524 reduced HBV-DNA and HbsAg levels in the supernatant with IC₅₀ values of 0.92 nM and 1.4 nM, respectively [1].

SAR107375 is a potent, orally active dual inhibitor of thrombin and factor Xa, with K_i values of 1 nM and 8 nM for factor Xa and thrombin, respectively [1].

SARS-CoV-2-IN-76 (compound 1) operates as an inhibitor of both nsp14-viral cap N7 methyltransferase and PLpro in severe acute respiratory syndrome coronavirus (SARS-CoV-2) [1].

SARS-CoV-2-IN-78 (compound 3) functions as an inhibitor of nsp14 in SARS-CoV-2 and exhibits antiviral properties through its activity as an N7 methyltransferase [1].