T8639

Phenibut hydrochloride (3-Amino-4-phenylbutyric acid hydrochloride) is a GABA mimetic that acts as an agonist at GABAB receptors, blocks α2δ subunit-containing voltage-gated calcium channels, stimulates dopamine receptors, and inhibits the actions of β-phenethylamine

EZH2-IN-18 (compound 9e) serves as a potent inhibitor of enhancer of zeste homologue 2 (EZH2 WT), exhibiting an IC50 of 1.01 nM. It effectively inhibits proliferation and induces apoptosis in tumor cells [1].