T8309

EIDD-2801 (Molnupiravir) is an isopropylester prodrug of the ribonucleoside analog N 4-hydroxycytidine (EIDD-1931) that has shown broad influenza virus and multiple coronaviruses activity.

HCT-116-IN-1, a γ-lactam-fused pyridone derivative, demonstrates significant anticancer properties with cytotoxicity towards HCT116 cells at an IC50 value of 5.59 μM [1].

Anticancer agent 113 possesses anticancer activity [1].

Anticancer agent 112[1], serves as a potent agent for cancer research.

Compound 107 (Compd 11jc) exhibits potent antitumor activity and serves as an effective anticancer agent in the investigation of pulmonary metastatic melanoma [1].

Compound 103 (Compound 2k) serves as a potent anticancer agent [1].

Anticancer Agent 101, a tetracaine derivative, exhibits anti-cancer activity [1].

Antibiofilm Agent-2 (Compound 4T) serves as a potent biofilm inhibitor, exhibiting an IC50 of 3.6 μM, and impairs the quorum sensing system along with iron homeostasis, acting as antibacterial synergists against Pseudomonas aeruginosa [1].

Antibacterial agent 165 (compound 3), a hydroxyquinoline derivative, effectively inhibits methicillin-resistant Staphylococcus aureus (MRSA) [1], demonstrating potent antibacterial properties.

Antibacterial agent 163 (compound 1), a hydroxyquinoline derivative, potently inhibits methicillin-resistant Staphylococcus aureus (MRSA) [1].

Antibacterial agent 162 trifluoromethanesulfonate (compound 7), a dual-function molecule, demonstrates potent inhibitory effects on Staphylococcus aureus, including MRSA strains, and exhibits antiproliferative activity against colon cancer and non-small cell lung cancer cells. This compound is applicable in both anticancer and antibacterial research [1].