T7693

Thiorphan is an neprilysin inhibitor (NEP; IC50 : 0.007 μM).

Bifarcept, a recombinant antibody targeting the interferon receptor type I (IFN-RI), enhances the serum half-life of IFN-β by facilitating its binding.

Birtamimab (NEOD001) is a monoclonal antibody selectively targeting and depleting amyloid protein, used in research on light chain amyloidosis.

Blontuvetmab (AT 004) is a canineized CD20 monoclonal antibody used for the research of canine B-cell lymphoma.

Botensilimab (AGEN 1181) is a humanized monoclonal antibody that specifically targets cytotoxic T-lymphocyte antigen 4 (CTLA-4). Botensilimab (AGEN 1181) functions as a potent activator of both innate and adaptive immune responses. Botensilimab (AGEN 1181) is under active research for its capacity to enhance antitumor immunity and modulate checkpoint pathways.

Brazikumab (AMG 139) is a humanized antibody targeting IL-23 by binding to the P19 subunit. It is a selective IL23p19 antagonist and can be used in Crohn's disease research.

Briakinumab (ABT-874) is a monoclonal antibody targeting IL-12, used in the study of psoriasis, rheumatoid arthritis, inflammatory bowel disease, and multiple sclerosis.

Budigalimab (ABBV 181) is a humanized monoclonal antibody targeting programmed cell death protein 1 (PD-1) with potential antitumor activity for the study of the anti-PD-1 inhibitor budigalimab in non-small cell lung cancer.

Burfiralimab (hzVSF-v13) is a monoclonal immunoglobulin (IgG4) targeted against waveform proteins, exhibiting anti-HBV properties and potential applications in rheumatoid arthritis research.

Camoteskimab (AVTX-007), a fully human, high-affinity anti-IL-18 monoclonal antibody, holds promise for research into autoinflammatory diseases, such as adult-onset Still's disease (AOSD) [1].

Cantuzumab mertansine (SB-408075; huC242-DM1), an antibody-drug conjugate (ADC), comprises the potent maytansine derivative (DM1) linked to the humanized monoclonal antibody (huC242) targeting CanAg. Demonstrating cytotoxicity against colon cancer cells, this compound shows extensive antitumor effectiveness across various CanAg-positive human tumor xenografts [1] [2].