T2769

3-Aminopropionitrile fumarate (2:1) [β-Aminopropionitrile fumarate] is an organic compound and antirheumatic agent utilized in veterinary medicine.

JTK-109 is a hepatitis C virus NS5B RNA-dependent RNA polymerase inhibitor with an IC₅₀ value of 0.017 μM. JTK-109 inhibits the G1b and G3a subgenomic replicases and the recombinase by targeting the Thumb-1 (T1) allosteric site of the NS5B polymerase. JTK-109 can be used in research on hepatitis C virus and cupovirus.

JNJ-DGAT1-A is a DGAT1-selective inhibitor.

JNJ-DGAT2-A, a specific inhibitor of DGAT2(IC50 = 0.14 μM), can be used in studies about the synthesis of triglycerides.

JPC-211 is an agonist of dopamine-receptor.

JTE-607 is a cytokine production inhibitor. JTE-607 induces apoptosis accompanied by an increase in p21waf1/cip1 in acute myelogenous leukemia cells.

JTT-552, a uric acid transporter 1 (URAT1) inhibitor, is used potentially for the treatment of hyperuricemia.

JTZ-951 is a potent and orally active inhibitor of hypoxia inducible factor prolyl hydroxylase (PHD).