T2238

Cariporide (HOE-642) (HOE-642), an effective NHE1 inhibitor, has inhibitory effects on the degranulation of human platelets, the formation of platelet-leukocyte-aggregates, and the activation of the GPIIb/IIIa receptor (PAC-1).

Norbenzetimide, an organic compound, is prepared from benzetimide by catalytic transfer hydrogenolysis.

Antimalarial agent 14 (NSC-102533) is a bioactive chemical.

NSC 31150 is a potential PPAR agonist with antibacterial, antidiabetic and antioxidant activities and may be used to study cancer and bacterial infections.

NSC 55655 (5-[(2-Nitrophenyl)methylene]-2,4-thiazolidinedione) possesses antimicrobial and antioxidant activities and inhibits the proliferation of B. subtilis, S. aureus, K. pneumonia, E. coli, S. typhi , A. niger and C. albicans. A. niger and C. albicans, and can be used in diabetes mellitus.

NSC 31153 is an apoptosis inhibitor and an effective Bax function inhibitor. It prevents Bax-mediated MOMP and cytochrome c release, used for cytoprotection and apoptosis research.

OBI-3424, a highly selective prodrug, is converted by aldo-keto reductase family 1 member C3 (AKR1C3) to a potent DNA-alkylating agent.

Cariporide Mesylate is a selective inhibitor of the Na+/H+ exchanger isoform 1.

Rostafuroxin (PST 2238) has been used in trials studying the treatment of Essential Hypertension.