T1669

Liothyronine Sodium is the sodium salt form of liothyronine, a synthetic form of the levorotatory isomer of the naturally occurring thyroid hormone triiodothyronine (T3). Liothyronine sodium (3,3',5-Triiodo-L-thyronine sodium) binds to nuclear thyroid receptors which then bind to thyroid hormone response elements of target genes. As a result, liothyronine sodium induces gene expression that is required for normal growth and development. Liothyronine sodium is more potent and has a more rapid action than thyroxine (T4).

Pyriproxyfen (S-31183) is an insecticide that acts as a biomimetic of juvenile hormone.

Pyrazofurin is a pyrimidine nucleoside analogue that potently inhibits cell proliferation and DNA synthesis by targeting UMP synthase, while also acting as a highly sensitive orotate-phosphoribosyltransferase inhibitor with IC50 values ranging from 0.06 to 0.37 μM in Hep-2, HNSCC-14B, and HNSCC-14C cell lines, supporting the use of Pyrazofurin as a mechanistic probe for nucleotide biosynthesis inhibition and antiproliferative research.

Pyrene-amido-PEG4-azide is a PEG-based proteolysis targeting chimera (PROTAC) linker used for the synthesis of PROTACs [1].

Pyrene-amido-PEG4-CH2CH2COOH is a polyethylene glycol (PEG) derived linker specifically designed for constructing proteolysis targeting chimeras (PROTACs)[1].

Pyrene-PEG5-alcohol is a PEG-based linker for PROTACs that connects two essential ligands, facilitating the formation of PROTAC molecules. This linker enables selective protein degradation by utilizing the ubiquitin-proteasome system within cells.

Pyridoclax is an inhibitor of potential Mcl-1.

Pyrintegrin, a β1-integrin agonist, promotes the survival of embryonic stem cells, can be used as a podocyte-protective agent, and enhances cell-extracellular matrix adhesion-mediated integrin signaling.

Pyronaridine tetraphosphate is an orally active, mannitol-containing inhibitor of DNA topoisomerase 2 and erythrocyte cytokine with antimalarial and antitumour activity.Pyronaridine tetraphosphate treats P. falciparum and Echinococcus granulosus infections. Pyronaridine tetraphosphate treats P. falciparum and Echinococcus granulosus infections and attenuates Ebola virus transmission.

PYZD-4409 is a selective UBA1 inhibitor with an IC50 of 20 μM. PYZD-4409 induces cell death in malignant cells and is preferentially cytotoxic to malignant cells over normal hematopoietic cells.

Liothyronine is a T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine.