T1398

Tadalafil (IC-351) is a carboline-based compound with vasodilatory activity that selectively inhibits the cyclic guanosine monophosphate (cGMP)-specific type 5 phosphodiesterase (PDE-5), preventing cGMP degradation in the smooth muscle of the corpus cavernosa and corpus spongiosum of the penis, thereby causing prolonged muscle relaxation, vasodilation, and enhanced penile erection.

(S)-Gossypol acetic acid ((S)-(+)-Gossypol acetic acid) is a conformational isomer of Gossypol that acts as a BH3 mimic capable of binding Bcl-xL and Bcl-2 proteins, with the potential to induce apoptosis and inhibit cell growth.

β-Naphthoflavone-CH2-Br is an arylhydrocarbon receptor (AhR) ligand. β-Naphthoflavone-CH2-Br used to synthesize the PROTAC β-NF-JQ1.

(±)-Befunolol is a blocking agent of β-adrenoceptor.

1,1,1-Trifluoroethyl-PEG2-azide is a PROTAC linker in the PEG class, used for synthesizing PROTAC molecules.

1,1,1-Trifluoroethyl-PEG4-alcohol is a polyethylene glycol (PEG) derivative typically used as a linker in the synthesis of protein degrader molecules, known as PROTACs [1].

111-Trifluoroethyl-PEG4-amine is a polyethylene glycol (PEG)-based linker appropriate for synthesizing proteolysis-targeting chimeras (PROTACs) [1].

1,1,1-Trifluoroethyl-PEG4-aminooxy is a polyethylene glycol (PEG)-based linker designed for the development of proteolysis targeting chimeras (PROTACs) [1].

111-Trifluoroethyl-PEG4-azide is a polyethylene glycol (PEG) derivative featuring a trifluoroethyl moiety and an azide functional group. It is utilized as a PROTAC linker, specifically designed for the synthesis of proteolysis-targeting chimeras (PROTACs)[1].

1,1,1-Trifluoroethyl-PEG4-Tos is a polyethylene glycol (PEG) derived linker molecule useful in the synthesis of Proteolysis Targeting Chimeras (PROTACs)[1].