T1279

Vilazodone (SB659746A) is a selective serotonin (5-HT) reuptake inhibitor (SSRI) and a 5-HT-1A receptor partial agonist, with antidepressant and anti-anxiety activities. Vilazodone inhibits the reuptake of serotonin from the synaptic cleft while stimulating the release of 5-HT into the synaptic cleft. This increases the concentration of 5-HT in the synaptic cleft and potentiates serotonergic neurotransmission in the central nervous system.

2,3,4,5-tetrahydroxypentyl (4E,8E,12E)-3,7-dihydroxy-2,4,6,8,10,12,14,16-octamethyl-11-{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}octadeca-4,8,12-trienoate is a high-purity biochemical reagent suitable for biochemical experiments and drug synthesis research.

2,3,4,5-tetrahydroxypentyl (2E,6E,10E)-5-hydroxy-2,4,6,8,10,12,14-heptamethyl-9-{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}hexadeca-2,6,10-trienoate is a high-purity biochemical reagent suitable for biochemical experiments and drug synthesis research.

(2E,4E)-6-({3-hydroxy-3,5-dimethyl-6-[(4E)-4-methylhex-4-en-2-yl]-2-oxooxan-4-yl}oxy)-6-oxohexa-2,4-dienoic acid is a high-purity biochemical reagent suitable for biochemical experiments and drug synthesis research.

(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl (1S,2R,4aS,6aS,6bR,10R,11R,12aR)-10,11-dihydroxy-1,2,6a,6b,9,9,12a-heptamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-4a-carboxylate is a high-purity biochemical reagent suitable for biochemical experiments and drug synthesis research.

(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl (4aS,6aS,6bR,10R,11R,12aR)-10,11-dihydroxy-2,2,6a,6b,9,9,12a-heptamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-4a-carboxylate is a high-purity biochemical reagent suitable for biochemical experiments and drug synthesis research.

(1S,3R,4S,5R)-1-(acetyloxy)-3,5-bis({[(2E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy})-4-hydroxycyclohexane-1-carboxylic acid is a high-purity biochemical reagent suitable for biochemical experiments and drug synthesis research.

(2S,3R,4E)-5-[2-({2-[(1E,3R,4S)-3,4-dihydroxypent-1-en-1-yl]-4-hydroxy-3-(hydroxymethyl)phenyl}methyl)-3-hydroxyphenyl]pent-4-ene-2,3-diol is a high-purity biochemical reagent suitable for biochemical experiments and drug synthesis research.

5-[(3E)-4-carboxy-3-methylbut-3-en-1-yl]-1,4a-dimethyl-6-methylidene-8-oxo-decahydronaphthalene-1-carboxylic acid is a high-purity biochemical reagent suitable for biochemical experiments and drug synthesis research.

(2S,3R,4S,5S,6R)-2-({2-[(2R,4aR,5R,8R)-5,8-dihydroxy-4a,8-dimethyl-decahydronaphthalen-2-yl]propan-2-yl}oxy)-6-(hydroxymethyl)oxane-3,4,5-triol is a high-purity biochemical reagent suitable for biochemical experiments and drug synthesis research.

(1R,3S,3aR,5aS,6S,9R,11aS,13aR)-1,6-dihydroxy-3a-(hydroxymethyl)-5a,8,8,11a,13a-pentamethyl-3-(propan-2-yl)-9-{[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-1H,2H,3H,3aH,4H,5H,5aH,5bH,6H,7H,7aH,8H,9H,10H,11H,11aH,13H,13aH,13bH-cyclopenta[a]chrysen-10-yl acetate is a high-purity biochemical reagent suitable for biochemical experiments and drug synthesis research.

2-[carboxy({[(2S,3R,4R,5R,6S)-4,5-dihydroxy-2-{[5-hydroxy-2-(4-methoxyphenyl)-8-(3-methylbut-2-en-1-yl)-4-oxo-7-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-4H-chromen-3-yl]oxy}-6-methyloxan-3-yl]oxy})methoxy]propanoic acid is a high-purity biochemical reagent suitable for biochemical experiments and drug synthesis research.

2-{[(2S,3R,4R,5R,6S)-4,5-dihydroxy-2-{[5-hydroxy-2-(4-methoxyphenyl)-8-(3-methylbut-2-en-1-yl)-4-oxo-7-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-4H-chromen-3-yl]oxy}-6-methyloxan-3-yl]oxy}-3-hydroperoxy-4-hydroxy-5-methyloxolane-3-carboxylic acid is a high-purity biochemical reagent suitable for biochemical experiments and drug synthesis research.

4b-hydroxy-1,4a,7-trimethyl-10-oxo-7-(2-{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}ethyl)-tetradecahydrophenanthrene-1-carboxylic acid is a high-purity biochemical reagent suitable for biochemical experiments and drug synthesis research.

3-hydroxy-12-(1-hydroxy-2-{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}ethyl)-2,6,12-trimethyl-15-oxatetracyclo[8.4.1.0^{1,10}.0^{2,7}]pentadecane-6-carboxylic acid is a high-purity biochemical reagent suitable for biochemical experiments and drug synthesis research.

1,5,12-trimethyl-9-oxo-5-(2-{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}ethyl)-8-oxatricyclo[9.4.0.0^{2,7}]pentadecane-12-carboxylic acid is a high-purity biochemical reagent suitable for biochemical experiments and drug synthesis research.

8a,9-dihydroxy-1,4a,7-trimethyl-7-(2-{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}ethyl)-tetradecahydrophenanthrene-1-carboxylic acid is a high-purity biochemical reagent suitable for biochemical experiments and drug synthesis research.

(3R)-8-hydroxy-3-methyl-5-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-3,4-dihydro-1H-2-benzopyran-1-one is a high-purity biochemical reagent suitable for biochemical experiments and drug synthesis research.

4-[7,8-bis(4-hydroxy-3-methoxybenzoyl)-1-(4-hydroxy-3-methoxyphenyl)-4-methylidene-2-oxaspiro[4.5]dec-7-en-3-yl]-2-methoxyphenol is a high-purity biochemical reagent suitable for biochemical experiments and drug synthesis research.

(2R,5S,7S,9S,10R,11E)-5-benzyl-9-hydroxy-7,14-dimethyl-8-methylidene-21-oxa-4-azatetracyclo[16.2.1.0^{2,6}.0^{2,10}]henicosa-1(20),11,18-trien-3-one is a high-purity biochemical reagent suitable for biochemical experiments and drug synthesis research.

(S)-Carvedilol is a non-selective β/α-1 blocker.It exerts protection against the vascular or cardiac toxicity of Doxorubicin (DOX).

RU-SKI 43 is a potent and selective hedgehog acyltransferase (Hhat) inhibitor with an IC50 of 850 nM. It exhibits anticancer activity and is a potential treatment for lung adenocarcinomas. RU-SKI 43 reduces Gli-1 activation through smoothening-independent non-canonical signaling and inhibits Akt and mTOR pathway activity.

Guadecitabine sodium is a inhibitor of second-generation DNA methyltransferases (DNMT) .

(2E,4E)-N-(1-hydroxy-3-methylpentan-2-yl)-2-methylhexa-2,4-dienamide is a high-purity biochemical reagent suitable for biochemical experiments and drug synthesis research.