T1258

Nabumetone (BRL14777)(BRL14777) is a non-steroidal anti-inflammatory drug and its active metabolite 6MNA inhibits the enzymes cyclo-oxygenase I and II.

PI3Kα/mTOR-IN-1 is a potent dual inhibitor of PI3Kα/mTOR, with an IC50 of 7 nM for PI3Kα in a cell assay and Kis of 12.5 nM and 10.6 nM for mTOR and PI3Kα [in a cell-free assay], respectively.

PTUPB is a potent dual inhibitor of sEH and COX-2 enzymes with IC50 values of 0.9 nM and 1.26 μM, respectively.

Ostruthin (Ostruthine) is a natural coumarin with antimicrobial activity that can effectively inhibit the growth of a wide range of mycobacteria with a minimum inhibitory concentration of MIC= 3.4-107.4 μM.

Puerarin-4'-O-β-D-glucopyranoside (Puerarin4'-O-glucoside) is a natural product isolated from Pueraria lobata root, exhibiting estrogenic activity and anti-proliferative effects in MCF-7 human breast carcinoma cells.

Zapotin is a natural polyhydroxylated flavonoid that inhibits K562 cells, E. coli, and HIV-1 RT RNase H, exhibiting antioxidant, antiviral, antibacterial, anticonvulsant, anticancer, anxiolytic, antifungal, and antidepressant-like activities.

Purpurogallin carboxylic acid is a natural product isolated from Macleaya microcarpa (Maxim.) Fedde, has anti-cancer activity.

PX20606 trans racemate is an agonist of FXR (EC50s of 32 and 34 nM for FXR in FRET and M1H assay, respectively).

Chlorajapolide F is a useful organic compound for research related to life sciences and the catalog number is T125830.

PXS-5120A is an irreversible fluoroallylamine Lysyl Oxidase-like 2/3 (LOXL2/3) inhibitor with anti-fibrotic activity.

Isomahanine is a useful organic compound for research related to life sciences and the catalog number is T125848.

PXS-5153A is an effective, selective, and fast-acting inhibitor of lysyl oxidase like 2/3 enzymes with enzymatic activity almost entirely blocked within 15 minutes. PXS-5153A could reduce crosslinks and ameliorates fibrosis.

Murrayanol is a useful organic compound for research related to life sciences and the catalog number is T125851.

Obscurolide A1 is a butenolide isolated from Streptomyces viridochromogenes cultures that shows weak inhibitory activity against Ca2+/CaM-dependent and non-Ca2+/CaM-dependent phosphodiesterases in cattle.

Py-MPB-amino-C3-PBD is a cytotoxic agent with a non-alkylating group and exhibits antimicrobial activity.

RA-XI is a natural product that can be used as a reference standard.

Pyridoxylamine (pyridoxamine) is an inhibitor of advanced glycation end production (AGEs) and lipoxidation end products (ALEs).

Dihydrocurcumenone is a useful organic compound for research related to life sciences and the catalog number is T125888.

Nitrocaphane, in combination with 5-FU (fluorouracil), chemotherapy is considered as a protocol of choice in the treatment of malignant trophoblastic tumor.