T1127

Beclometasone dipropionate (Vancenase) is the dipropionate ester of a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties. After cell surface receptor attachment and cell entry, beclomethasone enters the nucleus where it binds to and activates specific nuclear receptors, resulting in an altered gene expression and inhibition of proinflammatory cytokine production.

FG8119 is a novel benzodiazepine agonist with potential anticonvulsant and antiepileptic activity for studying neurological disorders.

Febuxostat-D9 is deuterium labeled Febuxostat (TMSM-3473), which is a selective xanthine oxidase inhibitor with Ki of 0.6 nM.

Fenclozine is a non-steroidal anti-inflammatory drug.

Fenmetozole Tosylate , acts as an antidepressant drug. is an antagonist of the actions of ethanol, also antagonizes α2-adrenergic receptor,

Fenpiverinium-D3 bromide is a deuterium labeled Fenpiverinium bromide.

Ferulenol, a sesquiterpene prenylated coumarin derivative, demonstrates potent antimycobacterial activity and [haemorrhagic] action by selectively targeting succinate ubiquinone reductase within the ubiquinone cycle.

Fesoterodine L-mandelate is a efficacious antimuscarinic agent for the overactive bladder (OAB).

Fexofenadine-D6 is the deuterium substituent of Fexofenadine (T21390) and can be used as an internal standard for the determination of non-sofenadine concentrations in human plasma.

FG 7142 (LSU-65) also modulates GABA-induced chloride flux at GABAA receptors expressing the α1 subunit (EC50= 137 nM). FG 7142 can increase tyrosine hydroxylation and cause upregulation of β-adrenoceptors in mouse cerebral cortex. FG 7142 , a non-selectively benzodiazepine inverse agonist, has high affinity for the α1 subunit-containing GABAA receptor (Ki=91 nM).

FGFR1/DDR2 inhibitor 1 is an inhibitor of discoidin domain receptor 2 (DDR2) and fibroblast growth factor receptor 1 (FGFR1), with IC50 values of 31.1 nM, 108.4 nM, and 3.2 nM for FGFR1, KG-1, and DDR2, respectively.

Beclomethasone Dipropionate-D6 is a deuterated compound of Beclomethasone Dipropionate. Beclomethasone Dipropionate (T1127) has a CAS number of 5534-09-8. Beclomethasone Dipropionate (T1127) is the dipropionate ester of a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties. After cell surface receptor attachment and cell entry, beclomethasone enters the nucleus where it binds to and activates specific nuclear receptors, resulting in an altered gene expression and inhibition of proinflammatory cytokine production.