T1013

Amikacin (Amikacina) is a broad-spectrum antibiotic derived from kanamycin.

(3S,5R)-Rosuvastatin is the (3R,5R)-enantiomer of Rosuvastatin, a competitive HMG-CoA reductase inhibitor with an IC50 of 11 nM.

4-Desmethoxy Omeprazole, the active metabolite of Omeprazole, acts as a proton pump inhibitor (PPI) and demonstrates competitive inhibition of CYP2C19 activity with a Ki of 2 to 6 μM.

(3S,5R)-Pitavastatin calcium is the enantiomer of Pitavastatin which is a potent HMG-CoA reductase inhibitor.

(3S,5S)-Pitavastatin calcium is the 3-epimer of Pitavastatin which is a potent HMG-CoA reductase inhibitor.

3'-Azido-3'-deoxy-5-methylcytidine inhibits HIV-1 reverse transcriptase (EC50 = 0.06 μM) and is an effective inhibitor of xenotropic murine leukemia-related retrovirus [XMRV, CC50 = 43.5 μM].

4,7,10,13,16-Docosapentaenoic acid (22:5n-6) is an endogenous metabolite [HMDB0002349], [CHEBI:32698], [CHEMBL113282], [PubChem CID: 3082141], that belongs to (non-methylene-interrupted polyunsaturated fatty acids) (NMIFA). This molecule is (biosynthesized from adrenate) and is classified as a (non-methylene interrupted fatty acid), (medium-chain fatty acid), and (DPA).

4-Acetamidophenyl acetate, an impurity of Acetaminophen, which is a selective COX-2 inhibitor (IC50: 25.8 μM) and a potent hepatic N-acetyltransferase 2 (NAT2) inhibitor.

4-Acetylsimvastatin is acetylated simvastatin. Simvastatin is a competitive inhibitor of HMG-CoA reductase (Ki: 0.2 nM).

4-Bromo A23187, a halogenated analog of the calcium ionophore A-23187, acts as a calcium modulator and induces apoptosis in various cells.

4-Desmethyl Istradefylline is a Istradefylline metabolite. Istradefylline is a very potent, selective, and orally active adenosine A2A receptor antagonist with Ki of 2.2 nM in experimental models of Parkinson's disease.