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Results for "
Ro 320432 hydrochloride
" in TargetMol Product Catalog- Inhibitors & Agonists2
Ro 32-0432 hydrochloride
T23244151342-35-7
Ro 32-0432 hydrochloride is a protein kinase C inhibitor.
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(s)-ro 32-0432
Ro 32-0432 hydrochloride
T847421781828-85-0
(S)-Ro 32-0432 is a potent, selective inhibitor of protein kinase C (PKC) and G protein-coupled receptor kinase 5 (GRK5), demonstrating ATP-competitive and oral activity. It presents IC50 values of 9.3 nM for PKCα, 28 nM for PKCβI, 30 nM for PKCβII, 36.5 nM for PKCγ, and 108.3 nM for PKCε, showcasing its effectiveness against multiple PKC isoforms. Additionally, (S)-Ro 32-0432 inhibits T-cell activation, indicating its potential application in the research of chronic inflammatory and autoimmune diseases [1] [2].
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