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Search Results for " ritonavir "

9

Compounds

Cat No. Product Name Synonyms Targets
T1525 Ritonavir RTV,Abbott 84538,A 84538,ABT 538 Apoptosis , SARS-CoV , HIV Protease
Ritonavir (ABT 538) is a peptidomimetic agent that inhibits both HIV-1 and HIV-2 proteases. Ritonavir is highly inhibited by serum proteins but boosts the effect of other HIV proteases by blocking their degradation by cy...
T12735 Ritonavir metabolite Desthiazolylmethyloxycarbonyl Ritonavir Others
Ritonavir metabolite is a Ritonavir metabolite, which is a inhibitor of HIV protease.
T74106 Hydroxy ritonavir
Hydroxy ritonavir, a metabolite of ritonavir, functions as an inhibitor of the HIV protease, thereby serving as a treatment for HIV infection and AIDS [1].
T22394 Paritaprevir ABT450,ABT-450,Veruprevir HCV Protease
Paritaprevir (ABT450) is an inhibitor of non-structural protein 3/4A protease with EC50 values of 1 and 0.21 nM for HCV 1a and HCV 1b, respectively.
T1623 Lopinavir ABT-378 SARS-CoV , HIV Protease
Lopinavir (ABT-378) is a peptidomimetic HIV protease inhibitor that retains activity against HIV protease with the Val 82 mutation. Lopinavir is less affected by binding to serum proteins than the structurally-related dr...
T64037 CYP3A4-IN-2
CYP3A4-IN-2 is a specific inhibitor of cytochrome P450 3A4 (CYP3A4) (IC50: 0.055 μM). CYP3A4-IN-2 is a ritonavir analogue with a more hydrophobic R2 side group and stronger inhibition than ritonavir. CYP3A4-IN-2 is capab...
T20562 Ureidovaline
Ureidovaline is an intermediate in the Ritonavir synthesis.
T64032 CYP3A4-IN-3
CYP3A4-IN-3 is a specific, highly affinity cytochrome P450 3A4 (CYP3A4) (cytochrome P450 3A4 (CYP3A4)) inhibitor (IC50: 0.075 μM). CYP3A4-IN-3 is an analogue of ritonavir with a simpler structure and twice as much inhibi...
T73898 Paritaprevir dihydrate
Paritaprevir dihydrate (ABT-450), a highly effective and orally administered antiviral, acts as a non-structural protein 3/4A (NS3/4A) protease inhibitor, displaying EC50 values of 1 and 0.21 nM against HCV genotypes 1a ...
TargetMol