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Polymyxin B-1

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Polymyxin B1
T125184135-11-9
Polymyxin B1, a potent antimicrobial lipopeptide derived from Bacillus polymyxa, has potential for treating multidrug-resistant Gram-negative bacterial infections.
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7-10 days
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Polymyxin B2 sulfate
T83903108965-69-1
Polymyxin B2, a significant component of polymyxin B, is an antibiotic cationic lipopeptide initially derived from B. polymyxa. This compound effectively inhibits P. aeruginosa, A. baumannii, K. pneumoniae, and E. cloacae strains, exhibiting minimum inhibitory concentrations (MICs) of 1-2, 0.5-1, 0.25-0.5, and 0.25-1 µg/ml, respectively. Notably, in a mouse model of P. aeruginosa bloodstream infection, administration of polymyxin B2 at a dosage of 4 mg/kg has been shown to decrease the number of colony-forming units (CFUs) in the blood.
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