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Cat No. | Product Name | Synonyms | Targets |
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T13015 | STING agonist-4 | STING | |
STING agonist-4 is an agonist of stimulator of Interferon Genes (STING) receptor(IC50 of 20 nM). | |||
T13613 | ChX710 | STING | |
ChX710 activates the type I interferon response to cytosolic DNA by priming specific Interferon-Stimulated Genes (ISGs), inducing the ISRE promoter sequence, and facilitating the phosphorylation of Interferon Regulatory ... | |||
T7329 | C-178 | STING | |
C-178 is a covalent inhibitor of STING, binds to Cys91 on STING to block its palmitoylation and prevents recruitment and phosphorylation of TBK1 in HEK293T cells. | |||
T9853 | STING activator Compound 53 | STING | |
STING activator Compound 53 based on an oxindole core structure demonstrated robust on-target functional activation of STING (human EC50 185 nM) in immortalised and primary cells and a cytokine induction fingerprint cons... | |||
T6919 | Omaveloxolone | RTA-408 | Apoptosis , Others , Nrf2 , STING |
Omaveloxolone (RTA-408) (RTA-408) is a synthetic triterpenoid that activates the cytoprotective transcription factor Nrf2 and inhibits NF-κB signaling. Phase 2. | |||
T9554 | SN-008 | STING | |
SN-008 is a less active analog SN-011 which is a STING antagonist. SN-008 can be used as a negative control. | |||
T5674 | H-151 | STING | |
H-151 is a highly potent and selective STING antagonist. H-151 covalently binds to Cys91 of STING and inhibits palmitoylation of Cys91, thereby inhibiting STING activity. H-151 can be used in the study of autoinflammator... | |||
T8655 | SR-717 | STING | |
SR-717 is a cGAMP analog, a non-nucleoside STING agonist that induces a "closed" activation conformation of STING. SR-717 has antitumor activity and promotes activation of immune cells and cross-presentation of antigens. | |||
T8798 | MSA-2 | STING | |
MSA-2 is a potent and orally available non-nucleotide STING agonist. | |||
T9029 | STING-IN-3 | C-171 | STING |
STING-IN-3 (C-171) is an inhibitor of stimulator of interferon genes (STING). It binds to STING, inhibits its palmitoylation, and prevents the recruitment and phosphorylation of TBK1. | |||
T5154 | C-176 | C176,STING inhibitor 1 | STING |
C-176 (STING inhibitor 1) is a strong, covalent mouse STING inhibitor | |||
T5516 | DiABZI STING agonist-1 trihydrochloride | STING | |
diABZI STING agonist-1 (trihydrochloride) is stimulator of interferon genes (STING) receptor agonist. | |||
T8328 | STING agonist-1 | G10 | Virus Protease , STING |
STING agonist-1 (G10) is a human-specific STING agonist,elicits antiviral activity against emerging Alphaviruses. | |||
T9028 | STING-IN-2 | C-170 | STING |
STING-IN-2 (C-170) is a potent and covalent inhibitor of STING. C-170 efficiently inhibits both mouse STING (mmSTING) and human STING (hsSTING). It can be used for autoinflammatory disease research. | |||
T7081 | CCCP | Carbonyl Cyanide m-Chlorophenylhydrazone,Carbonyl cyanide 3-chlorophenylhydrazone | Apoptosis , IκB/IKK , COX , Mitochondrial Metabolism , STING , IFNAR , Antibacterial |
CCCP (Carbonyl Cyanide m-Chlorophenylhydrazone) is an oxidative phosphorylation (OXPHOS) inhibitor and mitochondrial proton carrier uncoupler. CCCP inhibits the activation of STING and its downstream signaling molecules ... | |||
T9137 | SN-011 | [1,1'-Biphenyl]-4-carboxamide, N-[3-[[(4-fluorophenyl)sulfonyl]amino]-4-hydroxyphenyl]-,GUN35901 | STING |
SN-011 (GUN35901) is a STING inhibitor, which inhibited the activation of the STING signal pathway and to prevent or treat a STING- mediated disease. It is a demethyl analogue of DUN99845. | |||
T10252L2 | ADU-S100 ammonium salt | ML RR-S2 CDA ammonium salt,MIW815 ammonium salt | STING |
ADU-S100 ammonium salt (ML RR-S2 CDA ammonium salt) is an activator of stimulator of interferon genes (STING). ADU-S100 ammonium salt leads to potent and systemic tumor regression and immunity. | |||
T6273 | Vadimezan | DMXAA,5,6-Dimethylxanthenone-4-acetic Acid,NSC 640488,ASA-404 | Influenza Virus , VDA , STING , IFNAR |
Vadimezan (DMXAA) is a vascular disrupting agent, a murine STING agonist, and an inducer of cytokines such as type I IFN. Vadimezan has antitumor activity and induces a rapid cessation of blood flow in tumors without aff... | |||
T11035 | DiABZI STING agonist-1 (Tautomerism) | diABZI STING agonist (Compound 3) | STING |
diABZI STING agonist-1 (Tautomerism) (diABZI STING agonist (Compound 3)) is a selective stimulator of interferon genes (STING) receptor agonist, with EC50s of 130, 186 nM for human and mouse, respectively. | |||
T68087 | Inaperisone | Others | |
Inaperisone is a novel centrally acting muscle relaxant that inhibits the voiding reflex. Inaperisone may inhibit the voiding reflex by acting indirectly on GABAB receptors in the brainstem. | |||
T0511 | Tolperisone hydrochloride | Muscalm,Midocalm,Tolperisone HCl | Sodium Channel |
Tolperisone hydrochloride (Muscalm), a centrally acting muscle relaxant, is used in the therapy of pathologically increased tone of the cross-striated muscle resulted by neurological diseases (damage of the encephalomyel... | |||
T5005 | Eperisone hydrochloride | Others | |
Eperisone is a skeletal muscle relaxant and a spasmolytic agent related structurally to Tolperisone. | |||
T8441 | Lerisetron | 5-HT Receptor | |
Lerisetron is an antagonist of serotonin type 3 (5-HT3) receptor, with antiemetic activity. | |||
T70489 | Enerisant HCl | P450 , Histamine Receptor | |
Enerisant HCl is a novel potent and selective histamine H3 receptor antagonist, a substrate for P-gp, mediated by cytochrome P450 (CYP) and transporter proteins. | |||
T28778 | Silperisone HCl | RGH5002,SILA336,RGH-5002,Silperisone hydrochloride,SILA-336 | |
Silperisone HCl (RGH-5002) blocks sodium and calcium channels in cells, decreases excitability and contractility of muscle cells, reduces peripheral tone, and acts as a muscle relaxant and peripheral vasodilator. Silperi... | |||
T28159 | Nerisopam | EGIS-6775,GYKI 52322,GYKI52322,EGIS6775,GYKI-52322 | GABA Receptor |
Nerisopam is an agonist of gamma-aminobutyric acid (GABA) receptor. | |||
T32561 | Lanperisone | ||
Lanperisone is a muscle relaxant. | |||
T28160 | Nerispirdine HCl | HP-184,HP 184,Nerispirdine hydrochloride,HP184 | |
Nerispirdine is a acetylcholine release enhancer, sodium channel blocker and K(V) 2.1 channel blocker. Nerispirdine inhibits voltage-dependent Na(+) channel currents recorded from human SH-SY5Y cells with an IC(50) of 11... | |||
T124126 | Asteriscunolide A | ||
Asteriscunolide A is a useful organic compound for research related to life sciences and the catalog number is T124126. | |||
T40744 | Eperisone | ||
Eperisone is a centrally acting muscle relaxant and antispastic agent utilized in the treatment of conditions distinguished by muscle stiffness and pain. Its mechanism of action involves the relaxation of skeletal muscle... | |||
T21077 | Tolperisone free base | Mydeton,Atmosgen free base,Mideton,Menopatol,Besnoline free base,Mydocalm | |
Tolperisone free base, a centrally acting muscle relaxant, has been used for the symptomatic treatment of spasticity and muscle spasm. | |||
T71356 | Lanperisone HCl | ||
Lanperisone, also known as NK433, is a muscle relaxant. NK433 inhibited the facilitation of the flexor reflex mediated by group II afferent fibers that was induced by intrathecal administration of noradrenaline-HCl. NK43... | |||
T81509 | Perisulfakinin | ||
Perisulfakinin, a satiety-signaling neuropeptide, suppresses the activity of neurons that stimulate general activity [1]. | |||
T67828 | Enerisant | ||
Enerisant is an antagonist/inverse agonist of histamine H3 receptor.In vitro studies have shown that enerisant is a potent, highly selective, and competitive antagonist for the histamine H3 receptor, with a more than 3,0... | |||
T125082 | Pierisformoside B | ||
Pierisformoside B is a useful organic compound for research related to life sciences. The catalog number is T125082 and the CAS number is 308335-44-6. | |||
T125924 | Pterisolic acid B | ||
Pterisolic acid B is a useful organic compound for research related to life sciences and the catalog number is T125924. | |||
T71281 | Nerispirdine | ||
Nerispirdine is a biochemical that inhibits batrachotoxin binding to voltage-dependent sodium channels. | |||
T125921 | Monnieriside A | ||
Monnieriside A is a useful organic compound for research related to life sciences and the catalog number is T125921. |
Cat No. | Product Name | Synonyms | Targets |
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TN4843 | Pterisolic acid A | Others | |
Pterisolic acid A shows moderate activity against HCT-116,Hep G2 and BGC-823 cell lines. | |||
T81766 | Monnierisides A | ||
Monnierisides A, a chromone glycoside, has been isolated from Cnidium monnieri [1]. | |||
TN2056 | Perisesaccharide B | Others | |
Perisesaccharide B is a natural product | |||
TN1356 | Acetyl Perisesaccharide C | Others | |
Acetyl Perisesaccharide C is a natural product | |||
TN4846 | Pterisolic acid F | Others | |
Pterisolic acid F is a natural product from Pteris semipinnata. | |||
TN1948 | Monnieriside G | Others | |
Monnieriside G is a natural product from Cnidium monnieri. | |||
TN5576 | Pterisolic acid E | ||
Pterisolic acid E is a natural product from Pteris semipinnata. | |||
TN4845 | Pterisolic acid D | Others | |
Pterisolic acid D is a natural product for research related to life sciences. The catalog number is TN4845 and the CAS number is 1401419-88-2. | |||
TN2057 | Perisesaccharide C | Others | |
Perisesaccharide C is a natural product | |||
T83260 | 6β,7β-Epoxyasteriscunolide A | ||
6β,7β-Epoxyasteriscunolide A, a sesquiterpenoid, exhibits cytotoxicity against HL-60 and MOLT-3 leukemia cell lines, demonstrating half maximal inhibitory concentrations (IC50s) ranging from 4.1 to 5.4 μM [1]. | |||
TN4844 | Pterisolic acid C | Others | |
Pterisolic acid C is a natural product from Pteris semipinnata. |
Cat No. | Product Name | Species | Expression System |
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TMPH-00363 | Cyanovirin-N homolog Protein, Ceratopteris richardii, Recombinant (His) | Ceratopteris richardii | Yeast |
Mannose-binding lectin. |