Aminooxy-PEG2-azide

Aminooxy-PEG2-azide, a PEG-based PROTAC linker, is utilized for the synthesis of PROTACs[1] and serves as a non-cleavable 2-unit PEG ADC linker in the synthesis of antibody-drug conjugates (ADCs)[2].

t-Boc-Aminooxy-PEG2-azide is a polyethylene glycol (PEG) derived linker compound used for the synthesis of proteolysis targeting chimeras (PROTACs)[1].

Aminooxy-PEG2-bis-PEG3-BCN is a cleavable five-unit PEG ADC linker utilized in the creation of antibody-drug conjugates (ADCs) [1]. This compound also serves as a click chemistry reagent featuring a BCN group that undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing molecules.

Aminooxy-PEG2-BCN is a cleavable ADC linker that can be used in the synthesis of ADCs.Aminooxy-PEG2-BCN contains a BCN moiety and can undergo SPAAC click chemistry with molecules containing an Azide moiety.